About: The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Does Not Replicate in Syrian Hamsters

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Does Not Replicate in Syrian Hamsters Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Does Not Replicate in Syrian Hamsters
Creator	Munster, Vincent Feldmann, Heinz Bushmaker, Trenton Martellaro, Cynthia Baseler, Laura Haddock, Elaine Milne-Price, Shauna Prescott, Joseph Thomas, Tina Haagmans, Bart De Wit, Emmie Lackemeyer, Matthew
Source	Medline; PMC
abstract	In 2012 a novel coronavirus, MERS-CoV, associated with severe respiratory disease emerged in the Arabian Peninsula. To date, 55 human cases have been reported, including 31 fatal cases. Several of the cases were likely a result of human-to-human transmission. The emergence of this novel coronavirus prompts the need for a small animal model to study the pathogenesis of this virus and to test the efficacy of potential intervention strategies. In this study we explored the use of Syrian hamsters as a small animal disease model, using intratracheal inoculation and inoculation via aerosol. Clinical signs of disease, virus replication, histological lesions, cytokine upregulation nor seroconversion were observed in any of the inoculated animals, indicating that MERS-CoV does not replicate in Syrian hamsters.
has issue date	2013-07-02(xsd:dateTime)
bibo:doi	10.1371/journal.pone.0069127
bibo:pmid	23844250
has license	cc0
sha1sum (hex)	e6a9266f1f45099b19b5c4f3a4cf62de41786e54
schema:url	https://doi.org/10.1371/journal.pone.0069127
resource representing a document's title	The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Does Not Replicate in Syrian Hamsters
has PubMed Central identifier	PMC3699510
has PubMed identifier	23844250
schema:publication	PLoS One
resource representing a document's body	covid:e6a9266f1f45099b19b5c4f3a4cf62de41786e54#body_text
is schema:about of	named entity 'REPLICATE' named entity 'animal model' named entity 'Syrian Hamsters' named entity 'cases' named entity 'DOES NOT' named entity 'INDICATING' named entity 'NEED FOR' named entity 'POTENTIAL' named entity 'ANIMAL DISEASE MODEL' named entity 'DOES NOT' named entity 'OBSERVED' named entity 'EMERGENCE' named entity 'HUMAN' named entity 'HISTOLOGICAL' named entity 'ASSOCIATED WITH' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'PATHOGENESIS' named entity 'USE OF' named entity 'INCLUDING' named entity 'USING' named entity 'SYRIAN HAMSTERS' named entity 'PRESCOTT' named entity 'SEROCONVERSION' named entity 'RESPIRATORY DISEASE' named entity 'WIT' covid:arg/e6a9266f1f45099b19b5c4f3a4cf62de41786e54 named entity 'SYRIAN HAMSTERS' named entity 'INOCULATION' named entity 'VIRUS' named entity 'LIKELY' named entity 'REPORTED' named entity 'LESIONS' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'SMALL ANIMAL' named entity 'INTRATRACHEAL' named entity 'INTERVENTION STRATEGIES' named entity 'PROMPTS' named entity 'ANIMAL MODEL' named entity 'VIRUS REPLICATION' named entity 'ARABIAN PENINSULA' named entity 'NOVEL CORONAVIRUS' named entity 'UPREGULATION' named entity 'STUDY' named entity 'TO TEST' named entity 'MERS-COV' named entity 'DISEASE' named entity 'EFFICACY' named entity 'ANIMALS' named entity 'AEROSOL' named entity 'HAVE' named entity 'TRANSMISSION' named entity 'CITATION' named entity 'FATAL' named entity '287' named entity 'CASES' named entity 'SEVERE' named entity 'REPLICATE' named entity 'DATE' named entity 'CYTOKINE ' named entity 'RESULT' named entity 'signs' named entity 'replicate' named entity 'Arabian Peninsula' named entity 'result' named entity 'test' named entity 'The Middle' named entity 'upregulation' named entity 'emerged' named entity 'study' named entity 'strategies'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software