About: Botulinum toxin therapy in the SARS-CoV-2 pandemic: patient perceptions from a German cohort

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About: Botulinum toxin therapy in the SARS-CoV-2 pandemic: patient perceptions from a German cohort Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Botulinum toxin therapy in the SARS-CoV-2 pandemic: patient perceptions from a German cohort
Creator	Dressler, Dirk Fereshte, · Saberi, Adib
Source	Medline; PMC
abstract	The SARS-CoV-2 virus pandemic has provoked drastic countermeasures including shutdowns of public services. We wanted to describe the effects of a 6 week shutdown of a large German botulinum toxin (BT) outpatient clinics on patients and their well-being. 45 patients (age 61.9 ± 9.8 years, 29 females, 16 males) receiving BT therapy (319.3 ± 201.9MU-equivalent, treatment duration 8.3 ± 5.5 years) were surveyed with a standardised questionnaire. The shutdown delayed BT therapy by 6.6 ± 2.3 weeks. 93% of the patients noticed increased muscle cramps and 82% increased pain reducing their quality of life by 40.2 ± 19.5%. For 23 patients with cervical dystonia this reduction was 41.1 ± 18.3%, for 3 patients with blepharospasm 33.3 ± 15.3%, for 9 patients with spasticity 37.8 ± 15.6%, for 4 patients with pain conditions 37.4 ± 35.7% and for 3 patients with hemifacial spasm 27.5 ± 17.1%. After the shutdown 66% of patients perceived BT therapy as more important than before, 32% perceived it as unchanged. For all patients long-term availability of BT therapy was very important or important. 98% of the patients perceived the shutdown as inadequate and felt their patient rights not respected. The shutdown confirmed the considerable burden of disease caused by dystonia, spasticity, hemifacial spasm and various pain conditions and the importance of BT therapy to treat them. Any shutdown severely affects these patients and needs to be avoided.
has issue date	2020-07-30(xsd:dateTime)
bibo:doi	10.1007/s00702-020-02235-6
bibo:pmid	32734554
has license	cc-by
sha1sum (hex)	d199a27a04ef3f3907af1de60b6be76a2233e6d1
schema:url	https://doi.org/10.1007/s00702-020-02235-6
resource representing a document's title	Botulinum toxin therapy in the SARS-CoV-2 pandemic: patient perceptions from a German cohort
has PubMed Central identifier	PMC7391233
has PubMed identifier	32734554
schema:publication	J Neural Transm (Vienna)
resource representing a document's body	covid:d199a27a04ef3f3907af1de60b6be76a2233e6d1#body_text
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