About: Safety Profile of Musculoskeletal Contrast-Enhanced Ultrasound with Sulfur Hexafluoride Contrast Agent

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Safety Profile of Musculoskeletal Contrast-Enhanced Ultrasound with Sulfur Hexafluoride Contrast Agent
Creator	Doll, Julian Fischer, Christian Kunz, Pierre Strauch, Marten Weber, Marc-André
Source	Medline; PMC
abstract	PURPOSE: Muscle, bone and tendon regeneration depend on the microperfusion of the corresponding tissue which can be quantified with contrast-enhanced ultrasound (CEUS) using sulfur hexafluoride contrast agent (SonoVue(®)). This study investigated the incidence of adverse events (AEs) in musculoskeletal patients and gives an overview of musculoskeletal CEUS applications. PATIENTS AND METHODS: Based on 13 studies in a standardized monocentric setting, a total of 2268 CEUS examinations in 764 patients were performed and AEs due to the administration of sulfur hexafluoride contrast agent were classified as either mild, moderate or severe. RESULTS: No fatal events occurred. AEs were reported in three cases, of which only one was classified as severe and two as mild. The total rate of all AEs was 0.13% and 0.04% for severe AEs. CONCLUSION: The present analysis confirms the safety of musculoskeletal CEUS using sulfur hexafluoride contrast agent with a lower rate of AEs than that reported for other contrast agents even in elderly patients with concomitant diseases.
has issue date	2020-04-14(xsd:dateTime)
bibo:doi	10.2147/tcrm.s235235
bibo:pmid	32341645
has license	cc-by-nc
sha1sum (hex)	c574e17f6023130d5938bc69aa7ee94a0b931a9a
schema:url	https://doi.org/10.2147/tcrm.s235235
resource representing a document's title	Safety Profile of Musculoskeletal Contrast-Enhanced Ultrasound with Sulfur Hexafluoride Contrast Agent
has PubMed Central identifier	PMC7166060
has PubMed identifier	32341645
schema:publication	Ther Clin Risk Manag
resource representing a document's body	covid:c574e17f6023130d5938bc69aa7ee94a0b931a9a#body_text
is schema:about of	named entity 'performed' named entity 'authors' named entity 'depend' named entity 'regeneration' named entity 'Results' named entity 'Sulfur' named entity 'Hexafluoride' named entity 'REGENERATION' named entity 'EXAMINATIONS' named entity 'EITHER' named entity 'severe' named entity 'mild' named entity 'tendon' named entity 'metabolic disorder' named entity 'CEUS' named entity 'echogenic' named entity 'lungs' named entity 'CEUS' named entity 'liver' named entity 'increased blood pressure' named entity 'arthroplasty' named entity 'microbubbles' named entity 'CEUS' named entity 'AEs' named entity 'U.S.' named entity 'CEUS' named entity 'trauma surgeon' named entity 'osseous' named entity 'sulfur hexafluoride' named entity 'teres minor muscle' named entity 'prostate' named entity 'itching' named entity 'AEs' named entity 'sulfur hexafluoride' named entity 'frame rate' named entity 'sulfur hexafluoride' named entity 'safety profile' named entity 'Helsinki' named entity 'sulfur hexafluoride' named entity 'adverse events' named entity 'contrast agent' named entity 'Sulfur hexafluoride' named entity 'contrast agent' named entity 'hyperlipoproteinemia' named entity 'severe acute respiratory syndrome' named entity 'local anaesthetics' named entity 'perfusion' named entity 'hyperlipoproteinemia' named entity 'respiratory disease' named entity 'contrast agent' named entity 'AEs' named entity 'hypotension' named entity 'anaphylactic' named entity 'CEUS' named entity 'prednisolone' named entity 'internal medicine' named entity 'osseous' named entity 'MRI' named entity 'muscle' named entity 'headache' named entity 'antibiotics' named entity 'gadolinium' named entity 'contrast agent' named entity 'contrast agent' named entity 'CEUS' named entity 'sulfur hexafluoride' named entity '1, 2' named entity 'treatment of patients' named entity 'administered intravenously' named entity 'CEUS' named entity 'CEUS' named entity 'CEUS' named entity 'tendon' named entity 'gadolinium' named entity 'IDDM' named entity 'ultrasound' named entity 'perfusion'

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