About: Similar virus spectra and seasonality in paediatric patients with acute respiratory disease, Ghana and Germany

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Similar virus spectra and seasonality in paediatric patients with acute respiratory disease, Ghana and Germany
Creator	Corman, V Drexler, J Drosten, C Evans, J Panning, M Simon, A Annan, A Adu-Sarkodie, Y Annan, * Ebach, F Eis-Hübinger, A Krumkamp, R Kruppa, T May, J
Source	Elsevier; Medline; PMC
abstract	Abstract Epidemiological differences between tropical and temperate regions regarding viruses causing acute respiratory infection are poorly understood. This is in part because methodological differences limit the comparability of data from these two regions. Using identical molecular detection methods, we tested 1174 Ghanaian and 539 German children with acute respiratory infections sampled over 12 months for the 15 most common respiratory viruses by PCR. A total 43.2% of the Ghanaian and 56.6% of the German children tested positive for at least one respiratory virus. The pneumoviruses respiratory syncytial virus and human metapneumovirus were most frequently detected, in 13.1% and 25.1% within the Ghanaian and German children, respectively. At both study sites, pneumoviruses were more often observed at younger ages (p <0.001). In the Ghanaian rainy season, enveloped viruses were detected twice as often as non-enveloped viruses (prevalence rate ratio (PR) 2.0, 95% CI 1.7–2.4). In contrast, non-enveloped viruses were more frequent during the Ghanaian dry season (PR 0.6, 95% CI 0.4–0.8). In Germany, enveloped viruses were also more frequently detected during the relatively colder winter season (PR 1.6, 95% CI 1.2–2.1) and non-enveloped viruses during summer (PR 0.7, 95% CI 0.5–0.9). Despite a distance of about 5000 km and a difference of 44° latitude separating Germany and Ghana, virus spectra, age associations and seasonal fluctuation showed similarities between sites. Neither respiratory viruses overall, nor environmentally stable (non-enveloped) viruses in particular were more frequent in tropical Ghana. The standardization of our sampling and laboratory testing revealed similarities in acute respiratory infection virus patterns in tropical and temperate climates.
has issue date	2016-04-30(xsd:dateTime)
bibo:doi	10.1016/j.cmi.2015.11.002
bibo:pmid	26585774
has license	els-covid
sha1sum (hex)	c3e5b91b37442a67c9437de4d9c4ac77ae804cd3
schema:url	https://doi.org/10.1016/j.cmi.2015.11.002
resource representing a document's title	Similar virus spectra and seasonality in paediatric patients with acute respiratory disease, Ghana and Germany
has PubMed Central identifier	PMC7172147
has PubMed identifier	26585774
schema:publication	Clinical Microbiology and Infection
resource representing a document's body	covid:c3e5b91b37442a67c9437de4d9c4ac77ae804cd3#body_text
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