About: Community acquired respiratory virus infections in cancer patients—Guideline on diagnosis and management by the Infectious Diseases Working Party of the German Society for haematology and Medical Oncology

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About: Community acquired respiratory virus infections in cancer patients—Guideline on diagnosis and management by the Infectious Diseases Working Party of the German Society for haematology and Medical Oncology Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Community acquired respiratory virus infections in cancer patients—Guideline on diagnosis and management by the Infectious Diseases Working Party of the German Society for haematology and Medical Oncology
Creator	Berger, Annemarie Christopeit, Maximilian Hauf, Elke Hentrich, Marcus Kalkreuth, Jana Klein, Michael Kochanek, Matthias Lehners, Nicola Mayer, Karin Penack, Olaf Rieger, Christina Schalk, Enrico Silling, Gerda Vehreschild, Maria Weber, Thomas Wolf, Hans-Heinrich Von Lilienfeld-Toal, Marie Heussel, Claus
Source	Elsevier; Medline; PMC
abstract	Abstract Background Community acquired viruses (CRVs) may cause severe disease in cancer patients. Thus, efforts should be made to diagnose CRV rapidly and manage CRV infections accordingly. Methods A panel of 18 clinicians from the Infectious Diseases Working Party of the German Society for Haematology and Medical Oncology have convened to assess the available literature and provide recommendations on the management of CRV infections including influenza, respiratory syncytial virus, parainfluenza virus, human metapneumovirus and adenovirus. Results CRV infections in cancer patients may lead to pneumonia in approximately 30% of the cases, with an associated mortality of around 25%. For diagnosis of a CRV infection, combined nasal/throat swabs or washes/aspirates give the best results and nucleic acid amplification based-techniques (NAT) should be used to detect the pathogen. Hand hygiene, contact isolation and face masks have been shown to be of benefit as general infection management. Causal treatment can be given for influenza, using a neuraminidase inhibitor, and respiratory syncytial virus, using ribavirin in addition to intravenous immunoglobulins. Ribavirin has also been used to treat parainfluenza virus and human metapneumovirus, but data are inconclusive in this setting. Cidofovir is used to treat adenovirus pneumonitis. Conclusions CRV infections may pose a vital threat to patients with underlying malignancy. This guideline provides information on diagnosis and treatment to improve the outcome.
has issue date	2016-11-30(xsd:dateTime)
bibo:doi	10.1016/j.ejca.2016.08.015
bibo:pmid	27681877
has license	els-covid
sha1sum (hex)	bf49df2796b5ffe29995062a4359dbb926777bfc
schema:url	https://doi.org/10.1016/j.ejca.2016.08.015
resource representing a document's title	Community acquired respiratory virus infections in cancer patients—Guideline on diagnosis and management by the Infectious Diseases Working Party of the German Society for haematology and Medical Oncology
has PubMed Central identifier	PMC7125955
has PubMed identifier	27681877
schema:publication	European Journal of Cancer
resource representing a document's body	covid:bf49df2796b5ffe29995062a4359dbb926777bfc#body_text
is schema:about of	named entity 'WORKING' named entity 'intravenous immunoglobulins' named entity 'disease' named entity 'adenovirus' named entity 'respiratory syncytial virus' named entity 'haematology' named entity 'INFECTIOUS DISEASES' named entity 'MANAGEMENT' named entity 'PATIENTS' named entity 'TREATMENT' named entity 'RESULTS' named entity 'HAEMATOLOGY' named entity 'SOCIETY' named entity 'NEURAMINIDASE INHIBITOR' named entity 'DIAGNOSIS' named entity 'RECOMMENDATIONS' named entity 'LEAD' named entity 'CONTACT ISOLATION' named entity 'CLINICIANS' named entity 'COMMUNITY ACQUIRED' named entity 'PARTY' named entity 'TO DETECT' named entity 'RESPIRATORY SYNCYTIAL VIRUS' named entity 'PROVIDE' named entity 'MANAGE' named entity 'VITAL' named entity 'CONCLUSIONS' named entity 'INFLUENZA' named entity 'PNEUMONIA' named entity 'FACE MASKS' named entity 'NASAL' named entity 'INFECTION' named entity 'ASSOCIATED' named entity 'INCONCLUSIVE' named entity 'OUTCOME' named entity 'WORKING' named entity 'CANCER' named entity 'FOR DIAGNOSIS' named entity 'LITERATURE' named entity 'PANEL' named entity 'VIRUSES' named entity '30%' named entity 'GIVEN' named entity 'CASES' named entity 'AVAILABLE' named entity 'BEST' named entity 'BUT' named entity 'MEDICAL ONCOLOGY' named entity 'SETTING' named entity 'UNDERLYING' named entity 'ASSESS' named entity 'RAPIDLY' named entity 'CRV' named entity 'BENEFIT' named entity 'INTRAVENOUS IMMUNOGLOBULINS' named entity 'ADDITION' named entity 'MEDICAL ONCOLOGY' named entity 'GENERAL' named entity 'INFECTIONS' named entity 'PARAINFLUENZA VIRUS' named entity 'INCLUDING' named entity 'DATA' named entity 'METHODS' named entity 'RESPIRATORY VIRUS'

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