About: Virulent Avian Infectious Bronchitis Virus, People’s Republic of China

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About: Virulent Avian Infectious Bronchitis Virus, People’s Republic of China Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Virulent Avian Infectious Bronchitis Virus, People’s Republic of China
Creator	Liu, Xiaodong Hu, Yanxin Zhang, Guozhong Zhang, G Feng, Jinling Ma, Zhijun Yu, Qi Zhao, Jixun Feng, J Hu, Y Liu, X Ma, Z Yu, Q Zhao, J Husbandry, Animal Station Of Beijing, Veterinary
Source	PMC
abstract	A virulent avian infectious bronchitis virus (IBV) was isolated from 30-day-old broiler chickens that exhibited respiratory symptoms, nephropathologic lesions, and a high proportion of deaths in the People’s Republic of China during 2005. The strain, designated YN, was genetically and pathologically characterized. Phylogenetic analysis showed that YN and most of the previously characterized IBV isolates found in China were phylogenetically classified into 2 main genetic clusters. The YN isolate caused severe lesions and resulted in deaths of 65% in experimental infections of 30-day-old specific-pathogen–free chickens. Tracheal and severe kidney lesions developed in all infected birds, confirming the ability of YN strain to induce both respiratory and renal disease. IBV antigens were detected by immunohistochemical analysis in the trachea, lung, kidney, and bursa, consistent with histopathologic observations, virus isolation, and reverse transcription PCR detection. We showed that YN IBV exhibits severe pathogenicity in chickens, and that similar viruses are prevalent in China.
has issue date	2012-12-01(xsd:dateTime)
bibo:doi	10.3201/eid1812.120552
bibo:pmid	23171741
has license	no-cc
sha1sum (hex)	b9fbd0773ea09b1ad96a7746601d7a8e2125313d
schema:url	https://doi.org/10.3201/eid1812.120552
resource representing a document's title	Virulent Avian Infectious Bronchitis Virus, People’s Republic of China
has PubMed Central identifier	PMC3557894
has PubMed identifier	23171741
schema:publication	Emerg Infect Dis
resource representing a document's body	covid:b9fbd0773ea09b1ad96a7746601d7a8e2125313d#body_text
is schema:about of	named entity 'lung' named entity 'birds' named entity 'infections' named entity 'reverse transcription PCR' named entity 'developed' covid:arg/b9fbd0773ea09b1ad96a7746601d7a8e2125313d named entity 'prevalent' named entity 'China' named entity 'infectious bronchitis' named entity 'isolated' named entity 'histopathologic' named entity 'induce' named entity 'People' named entity 'experimental' named entity 'caused' named entity 'renal disease' named entity 'isolates' named entity 'IBV' named entity 'renal disease' named entity 'China' named entity 'China' named entity 'Tracheal' named entity 'kidney' named entity 'virulent' named entity 'serologically' named entity 'serotypes' named entity 'phylogenetic tree' named entity 'trachea' named entity 'stunting' named entity 'serotypes' named entity 'Nidovirales' named entity 'inoculation' named entity 'binding sites' named entity 'IBV' named entity 'vaccine' named entity 'allantoic' named entity 'IBV' named entity 'IBV' named entity 'Massachusetts' named entity 'Phylogenetic trees' named entity 'serotype' named entity 'serotype' named entity 'agarose gel electrophoresis' named entity 'China' named entity 'nucleotide' named entity 'infectious bronchitis' named entity 'gross pathologic' named entity 'reverse genetic' named entity 'hematoxylin' named entity 'Promega' named entity 'ClustalW' named entity 'renal tubular' named entity 'multiple alignment' named entity 'vaccine' named entity 'egg production' named entity 'protein' named entity 'histopathologic' named entity 'Trizol' named entity 'China' named entity 'PBS' named entity 'air sac' named entity 'Recombinant' named entity 'tissue tropism' named entity 'RT-PCR' named entity 'gene' named entity 'RT-PCR'

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