About: Multiple simultaneous viral infections in infants with acute respiratory tract infections in Spain

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Multiple simultaneous viral infections in infants with acute respiratory tract infections in Spain
Creator	Casas, Inmaculada Calvo, Cristina Pérez-Breña, Pilar Blanco, Carolina Frías, Elena Luz García-García, Maria Vázquez, Carmen
Source	Elsevier; Medline; PMC
abstract	BACKGROUND: The clinical significance of the presence of more than one type of virus in the respiratory specimens of children with respiratory infections is not clear. OBJECTIVES: To describe the clinical characteristics of multiple viral infections versus single infection by respiratory syncytial virus (RSV) in hospitalized infants. STUDY DESIGN: This is a prospective study conducted in all infants under 2 years of age admitted for acute respiratory infection (September 2000–June 2003) in a secondary teaching hospital. Virological diagnosis was made by two different multiplex reverse transcription-nested polymerase chain reaction (RT-PCR) assays in nasopharyngeal aspirates. We describe the clinical characteristics of the patients with multiple viral infections and compare them to a group of 86 randomly selected patients infected only with RSV. RESULTS: 749 specimens taken were analyzed. Respiratory viruses were detected in 65.9% of the samples. 86 children had multiple viral infections (17.4% of all positive specimens). The most frequent clinical diagnosis in this group was recurrent wheezing in 44% and bronchiolitis in 52%. Fever was significantly more frequent (p < 0.001), hospital stays were longer (p = 0.05), and antibiotic treatment was used more (p = 0.03) in infants with multiple viral infections than in the RSV-infected group. CONCLUSIONS: Multiple viral infections are frequent in hospitalized children with respiratory tract disease (17.4%). Multiple viral infections are linked to higher fever, longer hospital stays and more frequent use of antibiotics than in the case of infants with single RSV infections.
has issue date	2008-05-02(xsd:dateTime)
bibo:doi	10.1016/j.jcv.2008.03.012
bibo:pmid	18455958
has license	no-cc
sha1sum (hex)	b30f664e1392c4ab5e914ea75a8e57722a4e0641
schema:url	https://doi.org/10.1016/j.jcv.2008.03.012
resource representing a document's title	Multiple simultaneous viral infections in infants with acute respiratory tract infections in Spain
has PubMed Central identifier	PMC7108242
has PubMed identifier	18455958
schema:publication	J Clin Virol
resource representing a document's body	covid:b30f664e1392c4ab5e914ea75a8e57722a4e0641#body_text
is schema:about of	named entity 'antibiotic' named entity 'multiplex' named entity 'nasopharyngeal' named entity 'Multiple' named entity 'RESPIRATORY TRACT INFECTIONS' named entity 'MULTIPLE' named entity 'VIRUS' named entity 'STUDY DESIGN' named entity 'RESPIRATORY TRACT DISEASE' named entity 'NESTED POLYMERASE CHAIN REACTION' named entity 'RESPIRATORY INFECTIONS' named entity 'RECURRENT' named entity 'PRESENCE OF' named entity 'CONCLUSIONS' covid:arg/b30f664e1392c4ab5e914ea75a8e57722a4e0641 named entity 'SIMULTANEOUS' named entity 'UNDER 2 YEARS' named entity 'ANTIBIOTICS' named entity 'INFECTED' named entity 'TAKEN' named entity 'ACUTE RESPIRATORY INFECTION' named entity 'SECONDARY' named entity 'DIAGNOSIS' named entity 'JUNE' named entity 'PROSPECTIVE STUDY' named entity 'REVERSE TRANSCRIPTION' named entity 'RSV' named entity 'NASOPHARYNGEAL' named entity 'ANTIBIOTIC TREATMENT' named entity 'CHILDREN' named entity 'ACUTE' named entity 'DETECTED' named entity 'VIROLOGICAL' named entity '749' named entity 'DIFFERENT' named entity 'HIGHER' named entity 'TYPE' named entity 'SPAIN' named entity 'POSITIVE' named entity 'MORE THAN ONE' named entity 'HOSPITALIZED' named entity 'OBJECTIVES' named entity 'PATIENTS' named entity 'MULTIPLEX' named entity '0.03' named entity 'BRONCHIOLITIS' named entity 'FEVER' named entity 'A GROUP' named entity 'SINGLE INFECTION' named entity '2000' named entity 'INFANTS' named entity 'RESPIRATORY VIRUSES' named entity 'DESCRIBE' named entity 'TEACHING HOSPITAL' named entity 'CLINICAL DIAGNOSIS' named entity 'FREQUENT' named entity 'TO DESCRIBE' named entity 'USED' named entity 'RESPIRATORY SYNCYTIAL VIRUS' named entity 'HOSPITAL' named entity 'RESULTS' named entity 'CLINICAL CHARACTERISTICS' named entity 'VIRAL INFECTIONS' named entity 'USE OF' named entity 'CASE' named entity 'PCR' named entity 'IS A' named entity 'SAMPLES' named entity 'ADMITTED' named entity 'CLINICAL SIGNIFICANCE' named entity 'RESPIRATORY' named entity 'ANALYZED' named entity 'INFANTS' named entity 'CLEAR' named entity 'HOSPITALIZED CHILDREN'

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