About: Cerebral venous thrombosis in COVID-19-associated coagulopathy: A case report

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About: Cerebral venous thrombosis in COVID-19-associated coagulopathy: A case report Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Cerebral venous thrombosis in COVID-19-associated coagulopathy: A case report
Creator	Hara, Natsumi Motoyama, Arata Ouchi, Aiko Sugiyama, Yohsuke Takamoto, Takeshi Tanaka, Ryota Tsuchiya, Takaaki Yanagawa, Yoshitaka
Source	Elsevier; PMC
abstract	COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which was first reported in Wuhan, China in December 2019, and is ongoing pandemic. While a majority of patients with SARS-CoV-2 infection shows asymptomatic or mild disease, hospitalized patients can develop critical condition, such as pneumonia, sepsis, and respiratory failure. Some cases deteriorate into sever systemic disease and multiorgan failure. Many patients of severe COVID-19 show hypercoagulable state and complicate with venous thromboembolism and atrial thrombosis. We herein reported a case of COVID-19 who developed cerebral venous thrombosis (CVT) co-incidence with pulmonary thromboembolism (PTE). A 56-year-old Japanese man was presented with fever and malaise and diagnosed with COVID-19. He was treated with ciclesonide and azithromycin, but his respiratory condition deteriorated. Thus, systemic corticosteroids and favipiravir were initiated and these treatments resulted in afebrile state, improving malaise and respiratory failure. However, he suddenly developed severe headache and vomiting with increased concentration of D-dimer. Brain CT and MRI showed typical images of CVT in the left transvers sinus and CT pulmonary angiography showed PE. Administration of unfractionated heparin followed by edoxaban treatment reduced the levels of D-dimer and improved his clinical presentation and thrombosis. Monitoring coagulopathy is important in COVID-19 patients and in case of venous thromboembolism, including cerebral venous system, appropriate anticoagulant therapy should be initiated.
has issue date	2020-07-23(xsd:dateTime)
bibo:doi	10.1016/j.jocn.2020.07.038
has license	no-cc
sha1sum (hex)	ae7540b3a20489c2d85b6fa3df99417dd90a3d79
schema:url	https://doi.org/10.1016/j.jocn.2020.07.038
resource representing a document's title	Cerebral venous thrombosis in COVID-19-associated coagulopathy: A case report
has PubMed Central identifier	PMC7377797
schema:publication	J Clin Neurosci
resource representing a document's body	covid:ae7540b3a20489c2d85b6fa3df99417dd90a3d79#body_text
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