About: SARS-CoV-2-specific antibody detection in healthcare workers in Germany with direct contact to COVID-19 patients

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About: SARS-CoV-2-specific antibody detection in healthcare workers in Germany with direct contact to COVID-19 patients Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	SARS-CoV-2-specific antibody detection in healthcare workers in Germany with direct contact to COVID-19 patients
Creator	Dittmer, Ulf Krawczyk, Adalbert Anastasiou, Olympia Cordes, Sebastian Dolff, Sebastian Esser, Stefan Herrmann, Anke Jahn, Michael Korth, Johannes Kribben, Andreas Lindemann, Monika Ross, Birgit Wilde, Benjamin Witzke, Oliver
Source	Elsevier; Medline; PMC
abstract	BACKGROUND: The novel coronavirus SARS-CoV-2 is associated with a severe respiratory manifestation, COVID-19, and presents a challenge for healthcare systems worldwide. Healthcare workers are a vulnerable cohort for SARS-CoV-2 infection due to frequent and close contact to patients with COVID-19. STUDY DESIGN: Serum samples from 316 healthcare workers of the University Hospital Essen, Germany were tested for SARS-CoV-2-IgG antibodies. A questionnaire was used to collect demographic and clinical data. Healthcare workers were grouped depending on the frequency of contact to COVID-19 patients in high-risk-group (n = 244) with daily contact to known or suspected SARS-CoV-2 positive patients, intermediated-risk-group (n = 37) with daily contact to patients without known or suspected SARS-CoV-2 infection at admission and low-risk-group (n = 35) without patient contact. RESULTS: In 5 of 316 (1.6%) healthcare workers SARS-CoV-2-IgG antibodies could be detected. The seroprevalence was higher in the intermediate-risk-group vs. high-risk-group vs. 2/37 (5.4%) vs. (3/244 (1.2%), p = 0.13). Four of the five subject were tested negative for SARS-CoV-2 via PCR. One (20%) subject was not tested via PCR since he was asymptomatic. CONCLUSION: The overall seroprevalence of SARS-CoV-2 in healthcare workers of a tertiary hospital in Germany is low (1.6%). The data indicate that the local hygiene standard might be effective.
has issue date	2020-05-13(xsd:dateTime)
bibo:doi	10.1016/j.jcv.2020.104437
bibo:pmid	32434708
has license	no-cc
sha1sum (hex)	abbd06729b1f905f1e8e420dd9ec854afb341923
schema:url	https://doi.org/10.1016/j.jcv.2020.104437
resource representing a document's title	SARS-CoV-2-specific antibody detection in healthcare workers in Germany with direct contact to COVID-19 patients
has PubMed Central identifier	PMC7219425
has PubMed identifier	32434708
schema:publication	J Clin Virol
resource representing a document's body	covid:abbd06729b1f905f1e8e420dd9ec854afb341923#body_text
is schema:about of	named entity 'March' named entity 'healthcare' named entity 'N A' named entity 'tertiary hospital' named entity 'April' named entity 'COVID-19' named entity 'tertiary hospital' named entity 'University Hospital' named entity 'COVID' named entity 'direct contact' named entity 'Germany' named entity 'COVID-19' named entity 'SARS-CoV-2' named entity 'antibody' named entity 'Informed consent' named entity 'seroprevalence' named entity 'standard deviation' named entity 'asymptomatic infection' named entity 'seroprevalence' named entity 'healthcare workers' named entity 'route of transmission' named entity 'nasal swab' named entity 'seroprevalence' named entity 'context development' named entity 'antibody' named entity 'PCR' named entity 'SARS-CoV-2' named entity 'not-for-profit' named entity 'SARS-CoV-2' named entity 'vaccination' named entity 'hygiene' named entity 'healthcare workers' named entity 'Health care workers' named entity 'PCR' named entity 'SARS-CoV-2' named entity 'asymptomatic' named entity 'herd immunity' named entity 'ethics committee' named entity 'SARS-CoV-2' named entity 'hygiene' named entity 'COVID' named entity 'Germany' named entity 'Healthcare workers' named entity 'virus transmission' named entity 'IgG' named entity 'hygiene' named entity 'infection' named entity 'SARS' named entity 'antibody' named entity 'COVID' named entity 'PCR' named entity 'infection' named entity 'SARS-CoV-2' named entity 'asymptomatic' named entity 'COVID' named entity 'nasal swab' named entity 'Germany' named entity 'hygiene' named entity 'seroprevalence' named entity 'healthcare workers' named entity 'hygiene' named entity 'severe acute respiratory syndrome coronavirus 2' named entity 'staff infection' named entity 'seroprevalence' named entity 'tertiary hospital' named entity '3, 4' named entity 'Essen, Germany' named entity 'antibody'

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