About: Estimating the Asymptomatic Ratio of Norovirus Infection During Foodborne Outbreaks With Laboratory Testing in Japan

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About: Estimating the Asymptomatic Ratio of Norovirus Infection During Foodborne Outbreaks With Laboratory Testing in Japan Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Estimating the Asymptomatic Ratio of Norovirus Infection During Foodborne Outbreaks With Laboratory Testing in Japan
Creator	Nishiura, Hiroshi Matsuyama, Ryota Miura, Fuminari
Source	PMC
abstract	BACKGROUND: Foodborne norovirus outbreak data in Japan from 2005–2006, involving virological surveillance of all symptomatic and asymptomatic individuals, were reanalyzed to estimate the asymptomatic ratio of norovirus infection along with the risk of infection and the probability of virus shedding. METHODS: Employing a statistical model that is considered to capture the data-generating process of the outbreak and virus surveillance, maximum likelihood estimation of the asymptomatic ratio was implemented. RESULTS: Assuming that all norovirus outbreaks (n = 55) were the result of random sampling from an identical distribution and ignoring genogroup and genotype specificities, the asymptomatic ratio was estimated at 32.1% (95% confidence interval [CI], 27.7–36.7). Although not significant, separate estimation of the asymptomatic ratio of the GII.4 genotype appeared to be greater than other genotypes and was estimated at 40.7% (95% CI, 32.8–49.0). CONCLUSION: The present study offered the first explicit empirical estimates of the asymptomatic ratio of norovirus infection in natural infection settings. The estimate of about 30% was consistent with those derived from volunteer challenge studies. Practical difficulty in controlling GII.4 outbreaks was supported by the data, considering that a large estimate of the asymptomatic ratio was obtained for the GII.4 genotype.
has issue date	2018-09-05(xsd:dateTime)
bibo:doi	10.2188/jea.je20170040
bibo:pmid	29607886
has license	cc-by
sha1sum (hex)	a20dad1dae885e38b8aeadb93c22d14a54c6388a
schema:url	https://doi.org/10.2188/jea.je20170040
resource representing a document's title	Estimating the Asymptomatic Ratio of Norovirus Infection During Foodborne Outbreaks With Laboratory Testing in Japan
has PubMed Central identifier	PMC6111106
has PubMed identifier	29607886
schema:publication	J Epidemiol
resource representing a document's body	covid:a20dad1dae885e38b8aeadb93c22d14a54c6388a#body_text
is schema:about of	named entity 'ESTIMATING' named entity 'OUTBREAKS' named entity 'DIFFICULTY' named entity 'LARGE' named entity 'IDENTICAL' named entity 'RESULTS' named entity 'NATURAL INFECTION' named entity 'STUDIES' named entity 'GII' named entity 'SETTINGS' named entity 'METHODS' named entity 'NOROVIRUS' named entity 'ABOUT' named entity 'ESTIMATION' named entity 'VIRUS' named entity 'CONSIDERED' named entity 'RATIO' named entity 'PRESENT' named entity 'VOLUNTEER' named entity 'SUPPORTED' named entity 'EMPIRICAL' named entity 'EMPLOYING' named entity 'CONSISTENT WITH' named entity 'RESULT' named entity 'INVOLVING' named entity 'REANALYZED' named entity 'SURVEILLANCE' named entity 'STATISTICAL MODEL' named entity 'CHALLENGE' named entity 'CONFIDENCE INTERVAL' named entity 'RISK OF INFECTION' named entity 'GENOTYPE' named entity 'VIROLOGICAL' named entity 'GREATER THAN' named entity '30%' named entity 'CONCLUSION' named entity 'SYMPTOMATIC' named entity 'DATA' named entity 'GENERATING' named entity 'NOROVIRUS INFECTION' named entity 'ASYMPTOMATIC' named entity 'CAPTURE' named entity 'ESTIMATES' covid:arg/a20dad1dae885e38b8aeadb93c22d14a54c6388a named entity 'OBTAINED' named entity 'JAPAN' named entity 'DISTRIBUTION' named entity 'FOODBORNE' named entity 'FOODBORNE' named entity 'RATIO' named entity 'LABORATORY TESTING' named entity 'ASYMPTOMATIC' named entity 'NOROVIRUS INFECTION' named entity 'CONTROLLING' named entity 'GENOTYPES' named entity 'SPECIFICITIES' named entity 'ESTIMATE' named entity 'IMPLEMENTED' named entity 'RANDOM SAMPLING' named entity 'ESTIMATED' named entity 'OUTBREAK' named entity 'INDIVIDUALS' named entity 'NOT SIGNIFICANT' named entity 'MAXIMUM LIKELIHOOD ESTIMATION' named entity 'VIRUS SHEDDING' named entity 'OFFERED' named entity 'STUDY' named entity 'BACKGROUND' named entity 'DERIVED' named entity 'PROCESS' named entity 'JAPAN' named entity 'SEPARATE' named entity 'PROBABILITY OF' named entity 'genotype' named entity 'asymptomatic' named entity 'statistical model' named entity 'data-generating process' named entity 'norovirus' named entity 'genotypes'

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