About: Coronavirus disease 2019 in pregnancy

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Coronavirus disease 2019 in pregnancy
Creator	Shen, Xu Li, Gang Pan, Jian Jiang, Lei Yang, Weihua Lei, Zha Lingling, Pan Gang, Yang Guoping, Xiong Huang, Lingling Jian, Shen Lei, Guoping Lei, Huang Lu, Xiaogan Qiancheng, Xu Shirong, Li Wang, Shirong Weihua, Lu Xiaogan, Jiang Xiong, Zhen Zhen, Wang
Source	Elsevier; Medline; PMC; WHO
abstract	Abstract Objectives This study aims to compare clinical course and outcomes between pregnant and reproductive-aged non-pregnant women with COVID-19 and assess the vertical transmission potential of COVID-19 in pregnancy. Methods Medical records of pregnant and reproductive-aged non-pregnant women hospitalized with COVID-19 from January 15 to March 15, 2020, were retrospectively reviewed. The severity of disease, virus clearance time, and length of hospital stay were measured as the primary interest and the vertical transmission potential of COVID-19 was also assessed. Results Eighty-two patients (28 pregnant women, 54 reproductive-aged non-pregnant women) with laboratory confirmed COVID-19 were enrolled in this study. Univariate regression indicated no association between pregnancy and the severity of disease (OR 0.73, 95% CI 0.08-5.15; p =0.76), virus clearance time (HR 1.16, 95% CI 0.65-2.01; p =0.62), and length of hospital stay (HR 1.10, 95% CI 0.66-1.84; p =0.71). There were 22 pregnant women delivered 23 live births either by cesarean section (17, 60.7%) or vaginal delivery (5, 17.9%) and no neonate was infected with SARS-CoV-2. Conclusions Pregnant women have comparable clinical course and outcomes compared with reproductive-aged non-pregnant women when infected with SARS-CoV-2. No evidence supported vertical transmission of COVID-19 in the late stage of pregnancy including vaginal delivery.
has issue date	2020-04-27(xsd:dateTime)
bibo:doi	10.1016/j.ijid.2020.04.065
bibo:pmid	32353549
has license	els-covid
sha1sum (hex)	a1c2b98c6e09d08ae26856343069b9f790eee46d
schema:url	https://doi.org/10.1016/j.ijid.2020.04.065
resource representing a document's title	Coronavirus disease 2019 in pregnancy
has PubMed Central identifier	PMC7185021
has PubMed identifier	32353549
schema:publication	Int J Infect Dis
resource representing a document's body	covid:a1c2b98c6e09d08ae26856343069b9f790eee46d#body_text
is schema:about of	named entity 'pregnancy' named entity 'neonate' named entity 'This' named entity 'potential' named entity 'length' named entity 'delivered' named entity 'vaginal delivery' named entity 'medical' named entity 'WUHAN' named entity 'MEDICAL TEAM' named entity 'regression' named entity '95% CI' named entity 'January 15' named entity 'evidence' named entity 'vertical transmission' named entity 'virus' named entity 'Objectives' named entity 'Pregnant women' named entity 'Medical records' named entity 'vaginal delivery' named entity 'SARS-CoV-2' named entity 'cesarean section' named entity 'vaginal delivery' named entity 'non-pregnant' named entity 'non-pregnant' named entity 'statistical difference' named entity 'leukocytosis' named entity 'selection bias' named entity 'oxygen saturation' named entity 'COVID' named entity 'pregnant women' named entity 'virus' named entity 'Comorbidities' named entity 'pregnant women' named entity 'terminate the pregnancy' named entity 'neonate' named entity 'vertical transmission' named entity 'pregnant women' named entity 'respiratory distress syndrome' named entity 'pregnancy' named entity 'inhalation' named entity 'COVID' named entity 'infection' named entity 'SARS' named entity 'neonatal' named entity 'pregnant women' named entity 'pregnant women' named entity 'birthweight' named entity 'chest CT' named entity 'odds ratio' named entity 'pregnant women' named entity 'clinical symptoms' named entity 'Middle East' named entity 'Statistical Computing' named entity 'mg/dl' named entity 'pregnant women' named entity '0.80' named entity 'ordinal logistic regression' named entity 'clinical outcomes' named entity 'chest imaging' named entity 'umifenovir'

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