About: Alveolar fluid clearance in acute lung injury: what have we learned from animal models and clinical studies?

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Alveolar fluid clearance in acute lung injury: what have we learned from animal models and clinical studies?
Creator	Eickelberg, Oliver Morty, Rory Seeger, Werner Eickelberg, · Justus, · Morty, R
Source	PMC
abstract	BACKGROUND: Acute lung injury and the acute respiratory distress syndrome continue to be significant causes of morbidity and mortality in the intensive care setting. The failure of patients to resolve the alveolar edema associated with these conditions is a major contributing factor to mortality; hence there is continued interest to understand the mechanisms of alveolar edema fluid clearance. DISCUSSION: The accompanying review by Vadász et al. details our current understanding of the signaling mechanisms and cellular processes that facilitate clearance of edema fluid from the alveolar compartment, and how these signaling processes may be exploited in the development of novel therapeutic strategies. To complement that report this review focuses on how intact organ and animal models and clinical studies have facilitated our understanding of alveolar edema fluid clearance in acute lung injury and acute respiratory distress syndrome. Furthermore, it considers how what we have learned from these animal and organ models and clinical studies has suggested novel therapeutic avenues to pursue.
has issue date	2007-05-25(xsd:dateTime)
bibo:doi	10.1007/s00134-007-0662-7
bibo:pmid	17525842
has license	no-cc
sha1sum (hex)	9fee13458c2afb3c9dac6c04c0ccf070d703f54d
schema:url	https://doi.org/10.1007/s00134-007-0662-7
resource representing a document's title	Alveolar fluid clearance in acute lung injury: what have we learned from animal models and clinical studies?
has PubMed Central identifier	PMC7095514
has PubMed identifier	17525842
schema:publication	Intensive Care Med
resource representing a document's body	covid:9fee13458c2afb3c9dac6c04c0ccf070d703f54d#body_text
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