About: The Veterinary Immunological Toolbox: Past, Present, and Future

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The Veterinary Immunological Toolbox: Past, Present, and Future
Creator	Entrican, Gary Steinbach, Falko Hammond, John Faldyna, Martin Hope, Jayne Lunney, Joan Mwangi, William Jungersen, Gregers Wattegedera, Sean
Source	Medline; PMC
abstract	It is well-recognized that research capability in veterinary species is restricted by a lack of immunological reagents relative to the extensive toolboxes for small rodent biomedical model species and humans. This creates a barrier to the strategic development of disease control solutions for livestock, companion animals and wildlife that not only affects animal health but can affect human health by increasing the risk of transmission of zoonotic pathogens. There have been a number of projects aimed at reducing the capability gaps in the veterinary immunological toolbox, the majority of these focusing on livestock species. Various approaches have been taken to veterinary immunological reagent development across the globe and technological advances in molecular biology and protein biochemistry have accelerated toolbox development. While short-term funding initiatives can address specific gaps in capability, they do not account for long-term sustainability of reagents and databases that requires a different funding model. We review the past, present and future of the veterinary immunological toolbox with specific reference to recent developments discussed at the International Union of Immunological Societies (IUIS) Veterinary Immunology Committee (VIC) Immune Toolkit Workshop at the 12th International Veterinary Immunology Symposium (IVIS) in Seattle, USA, 16–19 August 2019. The future availability of these reagents is critical to research for improving animal health, responses to infectious pathogens and vaccine design as well as for important analyses of zoonotic pathogens and the animal /human interface for One Health initiatives.
has issue date	2020-07-28(xsd:dateTime)
bibo:doi	10.3389/fimmu.2020.01651
bibo:pmid	32849568
has license	cc-by
sha1sum (hex)	9da021101a9857c163fe89cf5e7ebd529462b5d5
schema:url	https://doi.org/10.3389/fimmu.2020.01651
resource representing a document's title	The Veterinary Immunological Toolbox: Past, Present, and Future
has PubMed Central identifier	PMC7399100
has PubMed identifier	32849568
schema:publication	Front Immunol
resource representing a document's body	covid:9da021101a9857c163fe89cf5e7ebd529462b5d5#body_text
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