About: The Roles of CCR7 for the Homing of Memory CD8+ T Cells into Their Survival Niches

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: The Roles of CCR7 for the Homing of Memory CD8+ T Cells into Their Survival Niches Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The Roles of CCR7 for the Homing of Memory CD8+ T Cells into Their Survival Niches
Creator	Woo, Yong
Source	Medline; PMC
abstract	Memory CD8+ T cells in the immune system are responsible for the removal of external Ags for a long period of time to protect against re-infection. Naïve to memory CD8+ T cell differentiation and memory CD8+ T cell maintenance require many different factors including local environmental factors. Thus, it has been suggested that the migration of memory CD8+ T cells into specific microenvironments alters their longevity and functions. In this review, we have summarized the subsets of memory CD8+ T cells based on their migratory capacities and described the niche hypothesis for their survival. In addition, the basic roles of CCR7 in conjunction with the migration of memory CD8+ T cells and recent understandings of their survival niches have been introduced. Finally, the applications of altering CCR7 signaling have been discussed.
has issue date	2020-05-20(xsd:dateTime)
bibo:doi	10.4110/in.2020.20.e20
bibo:pmid	32655968
has license	cc-by-nc
sha1sum (hex)	9d6ebfd4cae03d2d42deddfca140cbe932db49bb
schema:url	https://doi.org/10.4110/in.2020.20.e20
resource representing a document's title	The Roles of CCR7 for the Homing of Memory CD8+ T Cells into Their Survival Niches
has PubMed Central identifier	PMC7327150
has PubMed identifier	32655968
schema:publication	Immune Netw
resource representing a document's body	covid:9d6ebfd4cae03d2d42deddfca140cbe932db49bb#body_text
is schema:about of	named entity 'niches' named entity 'CD8+ T cells' named entity 'external' named entity 'memory' named entity 'subsets' named entity 'survival' named entity 'THEIR' named entity 'REMOVAL' named entity 'RECENT' named entity 'LONG' named entity 'T CELL' named entity 'CCR7' named entity 'responsible' named entity 'long' named entity 'migratory' named entity 'immune system' named entity 'T cell' named entity 'migration' named entity 'CD8+ T cell' named entity 'niche hypothesis' named entity 'CD8+ T cells' named entity 'microenvironments' named entity 'CCR7' named entity 'CCR7' named entity 'virus infection' named entity 'TCF1' named entity 'locus' named entity 'lymphocyte homing' named entity 'lungs' named entity 'high levels' named entity 'CCR7' named entity 'pathogens' named entity 'LCMV' named entity 'CCL19' named entity 'CCR7' named entity 'CD8+' named entity 'CD8+' named entity 'tightly regulated' named entity 'CCR7' named entity 'IL-15' named entity 'lung' named entity 'adaptive immune' named entity 'sulfation' named entity 'CCR7' named entity 'CCR7' named entity 'tumors' named entity 'virus' named entity 'CCL19' named entity 'littermate' named entity 'CD8+ T cells' named entity 'glycosylation' named entity 'wild-type' named entity 'innate response' named entity 'wild-type' named entity 'transgenic mice' named entity 'LCMV' named entity 'immune response' named entity 'small RNA' named entity 'B-lymphocytes' named entity 'CCR7' named entity 'gene methylation' named entity 'SLOs' named entity 'SLOs' named entity 'CD8+ T cells' named entity 'cytokines' named entity 'CCL21' named entity 'viral infections' named entity 'antigenic' named entity 'lung' named entity '7 transmembrane' named entity 'CCR7' named entity 'cytokines' named entity 'transcription factors' named entity 'CCR7' named entity 'SLOs' named entity 'spleen' named entity 'IL-7' named entity 'miR-21' named entity 'FRCs' named entity 'ligands' named entity 'downregulation'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software