About: Long non-coding RNAs and control of gene expression in the immune system

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Long non-coding RNAs and control of gene expression in the immune system
Creator	Fitzgerald, Katherine Atianand, Maninjay
Source	Elsevier; Medline; PMC
abstract	All cells of the immune system rely on a highly integrated and dynamic gene expression program that is controlled by both transcriptional and post-transcriptional mechanisms. Recently, non-coding RNAs, including long non-coding RNAs (lncRNA), have emerged as important regulators of gene expression in diverse biological contexts. Long non-coding RNAs control gene expression in the nucleus by modulating transcription or via post-transcriptional mechanisms targeting the splicing, stability or translation of mRNAs. Our knowledge of lncRNA biogenesis, their cell-type specific expressions, and their versatile molecular functions are rapidly progressing in all areas of biology. Here we discuss these exciting new regulators and highlight an emerging paradigm of lncRNA-mediated control of gene expression in the immune system.
has issue date	2014-11-01(xsd:dateTime)
bibo:doi	10.1016/j.molmed.2014.09.002
bibo:pmid	25262537
has license	green-oa
sha1sum (hex)	9c777e074b675d95be1c1da2790a788038c13e69
schema:url	https://doi.org/10.1016/j.molmed.2014.09.002
resource representing a document's title	Long non-coding RNAs and control of gene expression in the immune system
has PubMed Central identifier	PMC4252818
has PubMed identifier	25262537
schema:publication	Trends in Molecular Medicine
resource representing a document's body	covid:9c777e074b675d95be1c1da2790a788038c13e69#body_text
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