About: Isolation of a novel viral agent associated with porcine reproductive and neurological syndrome and reproduction of the disease

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Isolation of a novel viral agent associated with porcine reproductive and neurological syndrome and reproduction of the disease Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Isolation of a novel viral agent associated with porcine reproductive and neurological syndrome and reproduction of the disease
Creator	Schwartz, Kent Yoon, Kyoung-Jin Pogranichniy, Roman
Source	Elsevier; Medline; PMC
abstract	Disease outbreaks characterized by reproductive failure and/or neurologic disorders, which are commonly referred as “Porcine Reproductive and Neurologic Syndrome (PRNS)”, were observed in many swine farms in Iowa and other states. Although an infectious cause was suspected to account for the disease, no conclusive diagnosis had been reached with respect to conventional infectious agents. Extensive laboratory diagnostic investigation on suspect cases repeatedly resulted in the isolation of a cytopathic enveloped virus of 50–60 nm in size from nervous and second lymphoid tissues and sera and, to reflect its unknown identity, named “Virus X”. The presence of virus particle with morphological characteristics similar to Virus X in tissues from affected animals was also observed on thin-section positive-staining electron microscopy. Isolates of Virus X were not readily recognized by antibodies raised against any known viruses pathogenic to swine but by antisera collected from animals surviving clinical episode, indicating that Virus X is likely a previously unrecognized agent. Pregnant sows experimentally inoculated with Virus X (ISUYP604671) or homogenate (filtrate) of tissues from a clinically affected animal developed clinical signs and pathological changes similar to field observations including the loss of pregnancy. Furthermore, caesarian-derived, colostrum-deprived young pigs developed mild encephalomyelitis lesions in brains after experimental inoculation with the virus or the tissue homogenate although clinical neurologic signs were not observed. More importantly, Virus X was re-isolated from all inoculated animals while control pigs remained negative for the virus during the study. Collectively, Virus X is a novel viral agent responsible for PRNS and remains to be further characterized for taxonomical identity.
has issue date	2008-09-18(xsd:dateTime)
bibo:doi	10.1016/j.vetmic.2008.02.026
bibo:pmid	18406081
has license	no-cc
sha1sum (hex)	9bff79f6c866aa5c55d2368e5ddb92ea885b3717
schema:url	https://doi.org/10.1016/j.vetmic.2008.02.026
resource representing a document's title	Isolation of a novel viral agent associated with porcine reproductive and neurological syndrome and reproduction of the disease
has PubMed Central identifier	PMC7117417
has PubMed identifier	18406081
schema:publication	Vet Microbiol
resource representing a document's body	covid:9bff79f6c866aa5c55d2368e5ddb92ea885b3717#body_text
is schema:about of	named entity 'DISEASE' named entity 'ISOLATION' named entity 'PORCINE' named entity 'morphological' named entity 'antisera' named entity 'tissues' named entity 'recognized' named entity 'animals' named entity 'infectious agents' named entity 'encephalomyelitis' named entity 'inoculation' named entity 'viral' named entity 'CHARACTERISTICS' named entity 'VIRUS' named entity 'REFLECT' named entity 'EPISODE' named entity 'UNRECOGNIZED' named entity 'SERA' named entity 'CASES' named entity 'HOMOGENATE' named entity 'IDENTITY' named entity 'POSITIVE' named entity 'KNOWN' named entity 'LOSS OF PREGNANCY' named entity 'TISSUES' named entity 'AGENT' named entity 'NAMED' named entity 'REPEATEDLY' named entity 'BRAINS' named entity 'NEUROLOGIC' named entity 'VIRAL' named entity 'IS A' named entity 'ACCOUNT' named entity 'PRESENCE OF VIRUS PARTICLE' named entity 'NOT OBSERVED' named entity 'ELECTRON MICROSCOPY' named entity 'SIZE' named entity 'MILD' named entity 'LYMPHOID TISSUES' named entity 'NEUROLOGIC DISORDERS' named entity 'RESPECT' named entity 'SUSPECTED' named entity 'SWINE' named entity 'TISSUE' named entity 'MORPHOLOGICAL' named entity 'DIAGNOSTIC' named entity 'VIRUSES' named entity 'INVESTIGATION' named entity 'COLLECTED' named entity 'ANIMALS' named entity 'RAISED' named entity 'LABORATORY' named entity 'FARMS' named entity 'SECOND' named entity 'STUDY' named entity 'INDICATING' named entity 'VIRUS X' named entity 'INOCULATION' named entity 'FIELD' named entity 'SIMILAR' named entity 'REPRODUCTION' named entity 'ANTIBODIES' named entity 'NERVOUS' named entity 'OBSERVATIONS' named entity 'PREVIOUSLY' named entity 'CLINICAL' named entity 'IOWA' named entity 'PATHOLOGICAL' named entity 'AFFECTED' named entity 'EXTENSIVE' named entity 'NEUROLOGIC SIGNS' named entity 'ENCEPHALOMYELITIS' named entity 'LIKELY' named entity 'ANTISERA' named entity 'UNKNOWN' named entity 'SYNDROME' named entity 'COLOSTRUM' named entity 'OBSERVED' named entity 'NOVEL'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software