About: Small Animal Models for Human Immunodeficiency Virus (HIV), Hepatitis B, and Tuberculosis: Proceedings of an NIAID Workshop

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About: Small Animal Models for Human Immunodeficiency Virus (HIV), Hepatitis B, and Tuberculosis: Proceedings of an NIAID Workshop Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Small Animal Models for Human Immunodeficiency Virus (HIV), Hepatitis B, and Tuberculosis: Proceedings of an NIAID Workshop
Creator	Ploss, Alexander Wahl, Angela Subbian, Selvakumar Akkina, Ramesh Garcia, J Korba, Brent Endsley, Janice Barber, Daniel Bility, Moses Bissig, Karl-Dimiter Burwitz, Benjamin Eichelberg, Katrin Hafner, Richard Karakousis, Petros Koshy, Rajen Lambros, Chris Menne, Stephan Nuermberger, Eric Podell, Brendan Poluektova, Larisa Sanders-Beer, Brigitte
Source	PMC
abstract	The main advantage of animal models of infectious diseases over in vitro studies is the gain in the understanding of the complex dynamics between the immune system and the pathogen. While small animal models have practical advantages over large animal models, it is crucial to be aware of their limitations. Although the small animal model at least needs to be susceptible to the pathogen under study to obtain meaningful data, key elements of pathogenesis should also be reflected when compared to humans. Well‐designed small animal models for HIV, hepatitis viruses and tuberculosis require, additionally, a thorough understanding of the similarities and differences in the immune responses between humans and small animals and should incorporate that knowledge into the goals of the study. To discuss these considerations, the NIAID hosted a workshop on ‘Small Animal Models for HIV, Hepatitis B, and Tuberculosis’ on May 30, 2019. Highlights of the workshop are outlined below.
has issue date	2020-01-01(xsd:dateTime)
bibo:doi	10.2174/1570162x18666191223114019
bibo:pmid	31870268
has license	cc-by-nc
sha1sum (hex)	940019586ca9b5a2d47e5dcf0dd20815be467446
schema:url	https://doi.org/10.2174/1570162x18666191223114019
resource representing a document's title	Small Animal Models for Human Immunodeficiency Virus (HIV), Hepatitis B, and Tuberculosis: Proceedings of an NIAID Workshop
has PubMed Central identifier	PMC7403688
has PubMed identifier	31870268
schema:publication	Curr HIV Res
resource representing a document's body	covid:940019586ca9b5a2d47e5dcf0dd20815be467446#body_text
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