About: Nonrestorative Sleep, Musculoskeletal Pain, Fatigue in Rheumatic Disorders, and Allied Syndromes: A Historical Perspective

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Nonrestorative Sleep, Musculoskeletal Pain, Fatigue in Rheumatic Disorders, and Allied Syndromes: A Historical Perspective
Creator	Moldofsky, Harvey Moldofsky, H
Source	PMC
abstract	This chapter provides a historical perspective of the notion that the sleeping–waking brain is intimately related to complaints of unrefreshing sleep, widespread musculoskeletal pain, fatigue, and suffering. Such a constellation of symptoms extend from the remote biblical past, and involve various religious and cultural belief systems up to the recent evolution in Western medicine application of scientific methods for classification of illness. The contemporary application of scientific principles is directed to the etiology of diseases and to derive procedures for the management of such ill-understood illnesses. Historically, this constellation of rheumatic pain and fatigue symptoms have been given ever-changing medical and psychiatric labels that have been devoid of satisfactory medical understanding. In this chapter, the hypothesis that the sleeping/waking brain is integral to the somatic and behavioral symptoms of these disabling rheumatic chronic illness, termed fibromyalgia and various allied disorders, that are being examined and treated by a variety of health care professionals. Contemporary advances in mechanisms of how the sleeping–waking brain connects to these somatic and behavioral symptoms are reviewed. Potential avenues for further scientific understanding are described. Advances in such understanding are influencing current pharmacological and behavioral management of these suffering patients.
has issue date	2014-10-16(xsd:dateTime)
bibo:doi	10.1007/978-1-4939-2089-1_48
has license	no-cc
sha1sum (hex)	91be55f02caf0d2e1058a2446ca0bee5365673bc
schema:url	https://doi.org/10.1007/978-1-4939-2089-1_48
resource representing a document's title	Nonrestorative Sleep, Musculoskeletal Pain, Fatigue in Rheumatic Disorders, and Allied Syndromes: A Historical Perspective
has PubMed Central identifier	PMC7122008
schema:publication	Sleep Medicine
resource representing a document's body	covid:91be55f02caf0d2e1058a2446ca0bee5365673bc#body_text
is schema:about of	named entity 'SLEEP' named entity 'MUSCULOSKELETAL PAIN' named entity 'FATIGUE' named entity 'SYNDROMES' named entity 'PERSPECTIVE' named entity 'DISORDERS' named entity 'HISTORICAL' named entity 'Rheumatic Disorders' named entity 'Fatigue' named entity 'NREM sleep' named entity 'physiology' named entity 'somatic' named entity 'EEG' named entity 'chronic fatigue syndrome' named entity 'sleep deprivation' named entity 'SWS' named entity 'placebo-controlled' named entity 'musculoskeletal pain' named entity 'EEG' named entity 'neuroendocrine' named entity 'duloxetine' named entity 'Toronto' named entity 'metabolic' named entity 'insulin-like growth factor 1' named entity 'EEG' named entity 'William Gower' named entity 'EEG' named entity 'culture-bound' named entity 'scientific reports' named entity 'behavioral symptoms' named entity 'animal studies' named entity 'sleep quality' named entity 'path analysis' named entity 'sleep efficiency' named entity 'mass hysteria' named entity 'sleep deprivation' named entity 'behavioral symptoms' named entity 'histological' named entity 'hippocampi' named entity 'human behavior' named entity 'clinical features' named entity 'EEG' named entity 'stage 2' named entity 'SARS coronavirus' named entity 'poliomyelitis' named entity 'chest pain' named entity 'occipital region' named entity 'correlation' named entity 'posttraumatic stress' named entity 'SWS' named entity 'slow waves' named entity 'CNS' named entity 'fibromyalgia' named entity 'physiological' named entity 'melatonin' named entity 'musculoskeletal pain' named entity 'musculoskeletal pain' named entity 'medical knowledge' named entity 'XMRV' named entity 'insomnia' named entity 'susto' named entity 'hypersensitivity' named entity 'NREM sleep' named entity 'somatoform' named entity 'vitamins and minerals' named entity 'post-viral syndrome' named entity 'primary insomnia' named entity 'secretion' named entity 'REM sleep' named entity 'hypermotility' named entity 'diurnal' named entity 'apnea' named entity 'sleep stage' named entity 'SWS' named entity 'behavioral symptoms' named entity 'alpha activity' named entity 'analgesic' named entity 'gastrointestinal symptoms' named entity 'DSM-5' named entity 'negative affect' named entity 'ACC' named entity 'metabolites'

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