About: Viral channel forming proteins

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Viral channel forming proteins — Modeling the target Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Viral channel forming proteins — Modeling the target
Creator	Hsu, Hao-Jen Fischer, Wolfgang
Source	Elsevier; Medline; PMC
abstract	Abstract The cellular and subcellular membranes encounter an important playground for the activity of membrane proteins encoded by viruses. Viral membrane proteins, similar to their host companions, can be integral or attached to the membrane. They are involved in directing the cellular and viral reproduction, the fusion and budding processes. This review focuses especially on those integral viral membrane proteins which form channels or pores, the classification to be so, modeling by in silico methods and potential drug candidates. The sequence of an isolate of Vpu from HIV-1 is aligned with host ion channels and a toxin. The focus is on the alignment of the transmembrane domains. The results of the alignment are mapped onto the 3D structures of the respective channels and toxin. The results of the mapping support the idea of a ‘channel–pore dualism’ for Vpu.
has issue date	2011-02-28(xsd:dateTime)
bibo:doi	10.1016/j.bbamem.2010.05.014
bibo:pmid	20546700
has license	els-covid
sha1sum (hex)	84ed297ecc8750602dd8d5244d8699d44261e316
schema:url	https://doi.org/10.1016/j.bbamem.2010.05.014
resource representing a document's title	Viral channel forming proteins — Modeling the target
has PubMed Central identifier	PMC7094444
has PubMed identifier	20546700
schema:publication	Biochimica et Biophysica Acta (BBA) - Biomembranes
resource representing a document's body	covid:84ed297ecc8750602dd8d5244d8699d44261e316#body_text
is schema:about of	named entity 'The' named entity 'drug' named entity 'channels' named entity 'attached' named entity 'They' named entity 'idea' named entity 'target' named entity 'FUSION' named entity 'COMPANIONS' named entity 'CELLULAR' named entity 'IN SILICO METHODS' named entity 'TRANSMEMBRANE' named entity 'INVOLVED' named entity 'ALIGNMENT' named entity 'IMPORTANT' named entity 'ENCODED' named entity 'FORM' covid:arg/84ed297ecc8750602dd8d5244d8699d44261e316 named entity 'CHANNEL' named entity 'PROTEINS' named entity 'PROCESSES' named entity 'HIV-1' named entity 'MODELING' named entity 'TARGET' named entity 'FORMING' named entity 'STRUCTURES' named entity 'ION CHANNELS' named entity 'MEMBRANE PROTEINS' named entity 'PLAYGROUND' named entity 'MEMBRANES' named entity 'FOCUS' named entity 'ALIGNED WITH' named entity 'ACTIVITY' named entity 'IDEA' named entity 'ENCOUNTER' named entity 'ATTACHED TO' named entity 'MAPPED' named entity 'THEIR' named entity 'VIRAL MEMBRANE' named entity 'MEMBRANE' named entity 'VIRAL' named entity 'SIMILAR' named entity 'RESULTS' named entity 'SEQUENCE' named entity 'DRUG' named entity 'DUALISM' named entity 'POTENTIAL' named entity 'HOST' named entity 'INTEGRAL' named entity 'VPU' named entity 'CHANNELS' named entity 'BUDDING' named entity 'CLASSIFICATION' named entity 'REVIEW' named entity 'MODELING' named entity 'TOXIN' named entity 'MAPPING' named entity 'VIRAL REPRODUCTION' named entity 'SUPPORT' named entity 'VIRUSES' named entity 'ISOLATE' named entity 'modeling' named entity 'cellular' named entity 'Glu' named entity 'NMR studies' named entity 'perfect match' named entity 'monomer' named entity 'peptide' named entity 'KcsA' named entity 'KcsA' named entity 'channel protein' named entity 'protein' named entity 'HIV' named entity 'TMDs' named entity 'lipid membrane' named entity 'Vpu' named entity 'Vpu' named entity 'cytoplasmic' named entity 'MscL' named entity 'structural motif'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software