About: Viruses and atypical bacteria associated with asthma exacerbations in hospitalized children

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Viruses and atypical bacteria associated with asthma exacerbations in hospitalized children
Creator	Mistchenko, Alicia Barrero, Paola Fermepin, Marcelo Ferná Ndez, Francisco Fuse, Valentina Maffey, Alberto Saia, Mariana Teper, Alejandro Venialgo, Carolina Villalba, Analía
Source	Medline; PMC
abstract	OBJECTIVES AND WORKING HYPOTHESIS: To evaluate the prevalence of respiratory viruses Mycoplasma pneumoniae and Chlamydophila pneumoniae and gain insight into their seasonal circulation pattern in children with acute asthma exacerbations in a temperate southern hemisphere region. STUDY DESIGN: Patients hospitalized between 3 months and 16 years of age were included in a 1‐year prospective, observational, cross‐sectional study. Respiratory secretions were collected and the presence of different viruses and atypical bacteria analyzed by immunofluorescence and polymerase chain reaction. RESULTS: Two hundred nine patients (118 females) aged (mean ± SD) 4.4 ± 4 years were included. A potential causative agent was detected in 78% of the patients. The most frequently detected viruses were respiratory syncytial virus (HRSV) (n = 85; 40%) and rhinovirus (HRV) (n = 52; 24.5%); M. pneumoniae and C. pneumoniae were detected in 4.5% and 2% of the cases, respectively. Patients with HRSV (vs. HRV) were hospitalized for a longer time (6.7 vs. 5.2 days, P = 0.012), required more days of oxygen supply (5.1 vs. 3.4, P = 0.005), had a longer duration of the exacerbation before hospitalization (3.6 vs. 1.9 days, P = 0.001) and were younger (3.7 vs. 5.1 years, P = 0.012). Three peaks of admissions were observed. A first peak (early autumn) caused by HRV, a second peak (winter) caused mainly by HRSV and a third one (spring), caused by HRSV, an increase in HMPV together with a second outbreak of HRV. CONCLUSIONS: Children with an acute asthma exacerbation presented a high prevalence of respiratory viruses. Most hospitalizations corresponded to seasonal increases in prevalence of HRV and HRSV. Pediatr Pulmonol. 2010; 45:619–625. © 2010 Wiley‐Liss, Inc.
has issue date	2010-05-06(xsd:dateTime)
bibo:doi	10.1002/ppul.21236
bibo:pmid	20503289
has license	no-cc
sha1sum (hex)	7ff51224ea5e48b819c7b0b1074c5c62439fc7ca
schema:url	https://doi.org/10.1002/ppul.21236
resource representing a document's title	Viruses and atypical bacteria associated with asthma exacerbations in hospitalized children
has PubMed Central identifier	PMC7167758
has PubMed identifier	20503289
schema:publication	Pediatr Pulmonol
resource representing a document's body	covid:7ff51224ea5e48b819c7b0b1074c5c62439fc7ca#body_text
is schema:about of	named entity 'CONCLUSIONS' named entity 'ACUTE ASTHMA' named entity 'RESPIRATORY VIRUSES' named entity 'HOSPITALIZATION' named entity 'HIGH PREVALENCE' named entity 'CROSS-SECTIONAL STUDY' named entity 'MYCOPLASMA PNEUMONIAE' named entity '40%' covid:arg/7ff51224ea5e48b819c7b0b1074c5c62439fc7ca named entity 'atypical bacteria' named entity 'HRV' named entity '5.2' named entity 'causative agent' named entity 'polymerase chain reaction' named entity 'HMPV' named entity 'Mycoplasma pneumoniae' named entity 'asthma exacerbations' named entity 'HRV' named entity 'HRSV' named entity 'rhinovirus' named entity '5.1' named entity 'viruses' named entity 'HRV' named entity 'HEV' named entity 'wheezing' named entity 'statistical significance' named entity 'viruses' named entity 'respiratory symptoms' named entity 'Mycoplasma pneumoniae' named entity 'Pediatric Pulmonology' named entity 'Brescia' named entity 'asthmatic' named entity 'asthma' named entity 'M. pneumoniae' named entity 'HRV' named entity 'atypical bacteria' named entity 'oxygen' named entity '2.2' named entity 'Buenos Aires' named entity 'HPIV' named entity 'statistical significance' named entity 'chronic disease' named entity 'atopy' named entity 'polymerase chain reaction' named entity 'HRSV' named entity 'HEV' named entity 'atypical bacteria' named entity 'conjunctivitis' named entity 'HMPV' named entity 'premature birth' named entity 'false positive' named entity 'M. pneumoniae' named entity 'asthma' named entity 'atelectasis' named entity 'virus' named entity 'weeks of gestation' named entity 'respiratory symptoms' named entity 'oxygen supplementation' named entity 'HRSV' named entity 'RNA' named entity 'nasopharyngeal aspirate' named entity 'physical exam' named entity 'asthma' named entity 'HRSV' named entity 'clinical characteristics' named entity 'infection' named entity 'morbidity' named entity 'Allergies' named entity 'viruses' named entity 'acute exacerbations' named entity 'M. pneumoniae' named entity 'nebulized'

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