About: Clinical features and risk factors for ICU admission in COVID-19 patients with cardiovascular diseases

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About: Clinical features and risk factors for ICU admission in COVID-19 patients with cardiovascular diseases Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical features and risk factors for ICU admission in COVID-19 patients with cardiovascular diseases
Creator	He, Feng Lei, Ming Zeng, Jun Cao, Jie Liu, Riguang Qin, Shuguang Quan, Yibo Yang, Liuping Yu, Na Zhao, Ziwen
Source	Medline; PMC
abstract	Previous studies on coronavirus disease 2019 (COVID-19) have focused on the general population. However, cardiovascular disease (CVD) is a common comorbidity that has rarely been investigated in detail. This study aims to describe clinical characteristics and determine risk factors for intensive care unit (ICU) admission of COVID-19 patients with CVD. In this retrospective cohort study, we included 288 adult patients with COVID-19 in Guangzhou Eighth People's Hospital from January 15, 2020 to March 10, 2020. Demographic characteristics, laboratory results, radiographic findings, complications, and treatments were recorded and compared between CVD and non-CVD groups. A binary logistic regression model was used to identify risk factors associated with ICU admission for infected patients with underlying CVD. COVID-19 patients in the CVD group were older and had higher levels of troponin I (TnI), C-reactive protein (CRP), and creatinine. They were also more prone to develop into severe or critically severe cases, receive ICU admission, and require respiratory support treatment. Multivariate regression analysis showed that the following were risk factors for ICU admission in COVID-19 patients with CVD: each 1-year increase in age (odds ratio (OR), 1.08; 95% confidence interval (CI), 1.02-1.17; p = 0.018); respiratory rate over 24 times per min (OR, 25.52; 95% CI, 5.48-118.87; p < 0.0001); CRP higher than 10 mg/L (OR, 8.12; 95% CI, 1.63-40.49; p = 0.011); and TnI higher than 0.03 μg/L (OR, 9.14; 95% CI, 2.66-31.43; p < 0.0001). Older age, CRP greater than 10 mg/L, TnI higher than 0.03 μg/L, and respiratory rate over 24 times per minute were associated with increasing odds of ICU admission in COVID-19 patients with CVD. Investigating and monitoring these factors could assist in the risk stratification of COVID-19 patients with CVD at an early stage.
has issue date	2020-07-23(xsd:dateTime)
bibo:doi	10.14336/ad.2020.0622
bibo:pmid	32765943
has license	cc-by
sha1sum (hex)	7f3e1ff7e587d2e3b3390f15133fe843f38d9c98
schema:url	https://doi.org/10.14336/ad.2020.0622
resource representing a document's title	Clinical features and risk factors for ICU admission in COVID-19 patients with cardiovascular diseases
has PubMed Central identifier	PMC7390529
has PubMed identifier	32765943
schema:publication	Aging Dis
resource representing a document's body	covid:7f3e1ff7e587d2e3b3390f15133fe843f38d9c98#body_text
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