About: Substantial underestimation of SARS-CoV-2 infection in the United States due to incomplete testing and imperfect test accuracy

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About: Substantial underestimation of SARS-CoV-2 infection in the United States due to incomplete testing and imperfect test accuracy Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Substantial underestimation of SARS-CoV-2 infection in the United States due to incomplete testing and imperfect test accuracy
Creator	Hsiang, Michelle Hubbard, Alan Arnold, Benjamin Colford, John Wu, Sean Benjamin-Chung, Jade Crider, Yoshika Djajadi, Stephanie Mertens, Andrew Nguyen, Anna Pokpongkiat, Nolan Reingold, Art Seth, Anmol
Source	MedRxiv
abstract	Accurate estimates of the burden of SARS-CoV-2 infection are critical to informing pandemic response. Current confirmed COVID-19 case counts in the U.S. do not capture the total burden of the pandemic because testing has been primarily restricted to individuals with moderate to severe symptoms due to limited test availability. Using a semi-Bayesian probabilistic bias analysis to account for incomplete testing and imperfect diagnostic accuracy, we estimated 6,275,072 cumulative infections compared to 721,245 confirmed cases (1.9% vs. 0.2% of the population) as of April 18, 2020. Accounting for uncertainty, the number of infections was 3 to 20 times higher than the number of confirmed cases. 86% (simulation interval: 64-99%) of this difference was due to incomplete testing, while 14% (0.3-36%) was due to imperfect test accuracy. Estimates of SARS-CoV-2 infections that transparently account for testing practices and diagnostic accuracy reveal that the pandemic is larger than confirmed case counts suggest.
has issue date	2020-05-18(xsd:dateTime)
bibo:doi	10.1101/2020.05.12.20091744
has license	medrxiv
sha1sum (hex)	7d37959a44c69f0cd8a618e0e39cbee06116f010
schema:url	https://doi.org/10.1101/2020.05.12.20091744
resource representing a document's title	Substantial underestimation of SARS-CoV-2 infection in the United States due to incomplete testing and imperfect test accuracy
resource representing a document's body	covid:7d37959a44c69f0cd8a618e0e39cbee06116f010#body_text
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