About: Host Single-Nucleotide Polymorphisms and Altered Responses to Inactivated Influenza Vaccine

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About: Host Single-Nucleotide Polymorphisms and Altered Responses to Inactivated Influenza Vaccine Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Host Single-Nucleotide Polymorphisms and Altered Responses to Inactivated Influenza Vaccine
Creator	Edwards, Kathryn Li, Haijing Tang, Yi-Wei Shyr, Yu Wu, Huiyun
Source	PMC
abstract	We analyzed the relationship between host gene polymorphisms and responses in recipients of inactivated influenza vaccine, who were classified into poor, normal, or adverse response groups. The frequency of the mannose-binding lectin-2 codon 54 allele was significantly different among the 3 types of responders, with a decreased odds ratio for the development of poor or adverse responses (P = .033). There was no statistical relationship between responses and either tumor necrosis factor-α or interleukin (IL)-10 promoter polymorphisms among the 3 response groups. When poor and normal responses were combined, the -1082 A allele in the IL-10 promoter conferred a significantly decreased risk of the development of adverse responses (P = .041). These data indicate that host polymorphisms play a role in determining responses to influenza vaccine.
has issue date	2007-10-01(xsd:dateTime)
bibo:doi	10.1086/521370
bibo:pmid	17763324
has license	no-cc
sha1sum (hex)	7adcc0767cfc5fe2774feba898463b6ed3738413
schema:url	https://doi.org/10.1086/521370
resource representing a document's title	Host Single-Nucleotide Polymorphisms and Altered Responses to Inactivated Influenza Vaccine
has PubMed Central identifier	PMC7111848
has PubMed identifier	17763324
schema:publication	J Infect Dis
resource representing a document's body	covid:7adcc0767cfc5fe2774feba898463b6ed3738413#body_text
is schema:about of	named entity 'HOST' named entity 'gene' named entity 'response' named entity 'responses' named entity 'influenza vaccine' named entity 'DEVELOPMENT' named entity 'RELATIONSHIP' named entity 'ANALYZED' named entity 'PLAY' named entity 'IL-10' named entity 'CODON' named entity 'EITHER' named entity 'INACTIVATED INFLUENZA VACCINE' named entity 'CLASSIFIED' named entity 'RISK OF' named entity 'INACTIVATED INFLUENZA VACCINE' named entity 'SINGLE-NUCLEOTIDE POLYMORPHISMS' named entity 'DATA' named entity 'STATISTICAL' named entity 'INTERLEUKIN ' named entity 'ALTERED' named entity 'RESPONSES' named entity 'PROMOTER' named entity 'RESPONSE' named entity 'POOR' named entity 'MANNOSE-BINDING LECTIN' named entity 'POLYMORPHISMS' named entity 'GROUPS' named entity 'DIFFERENT' named entity 'ALLELE' named entity 'NORMAL' named entity 'ODDS RATIO' named entity 'GENE POLYMORPHISMS' named entity 'THESE' named entity 'TUMOR NECROSIS FACTOR' named entity 'ROLE' named entity '3 TYPES' named entity 'HOST' named entity 'FREQUENCY' named entity 'COMBINED' named entity 'INFLUENZA VACCINE' named entity 'RESPONSES' named entity 'DECREASED' covid:arg/7adcc0767cfc5fe2774feba898463b6ed3738413 named entity 'polymorphisms' named entity 'groups' named entity 'combined' named entity 'tumor' named entity 'normal' named entity 'odds ratio' named entity 'polymorphisms' named entity 'data' named entity 'Vaccine' named entity 'polymorphisms' named entity 'gene' named entity 'statistical relationship' named entity 'polymorphisms' named entity 'influenza vaccine' named entity 'odds ratio' named entity 'Single-Nucleotide Polymorphisms' named entity 'transcriptional regulation' named entity 'PCR' named entity 'immunogenicity' named entity 'TaqMan' named entity 'bivalent' named entity 'immunomodulator' named entity 'H1N1' named entity 'promoter region' named entity 'exon' named entity 'promoter region' named entity 'single-nucleotide polymorphisms' named entity 'allele' named entity 'PCR' named entity 'IL-10' named entity 'immunogenetic' named entity 'promoter regions' named entity 'alleles'

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