About: The Role of ErbB Receptors in Infection

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The Role of ErbB Receptors in Infection
Source	Elsevier; Medline; PMC
abstract	Members of the epidermal growth factor receptor family (ErbB family) possess a wide distribution and diverse functions ranging from cellular growth to migration and apoptosis. Though highly implicated in a variety of cancers, their involvement in infectious disease is less recognised. A growing body of evidence now highlights the importance of the ErbB family in a variety of infections. Their role as growth factor receptors, along with other characteristics, such as surface expression and continuous intracellular trafficking, make this receptor family ideally placed for exploitation by pathogens. Herein, we review our current understanding of the role of the ErbB family in the context of infectious disease, exploring the mechanisms that govern pathogen exploitation of this system.
has issue date	2017-11-30(xsd:dateTime)
bibo:doi	10.1016/j.tim.2017.04.009
bibo:pmid	28522156
has license	els-covid
sha1sum (hex)	73444e7dd59a091ead0d60cc662fdd5d22019b2f
schema:url	https://doi.org/10.1016/j.tim.2017.04.009
resource representing a document's title	The Role of ErbB Receptors in Infection
has PubMed Central identifier	PMC7126822
has PubMed identifier	28522156
schema:publication	Trends in Microbiology
resource representing a document's body	covid:73444e7dd59a091ead0d60cc662fdd5d22019b2f#body_text
is schema:about of	named entity 'infection' named entity 'HBV' named entity 'hepatoma' named entity 'TGF-b' named entity 'nucleus' named entity 'oncogenic virus' named entity 'heatshock protein' named entity 'HPV' named entity 'AnxA2' named entity 'cell cycle' named entity 'correlation' named entity 'EGFR' named entity 'translocation' named entity 'EGFR' named entity 'malignancies' named entity 'ErbB' named entity 'Helicobacter pylori' named entity 'pathogen' named entity 'ErbB2' named entity 'protein kinase' named entity 'phosphoinositide' named entity 'cancer therapies' named entity 'ligands' named entity 'b-catenin' named entity 'oncogenic viruses' named entity 'EGFR' named entity 'risk factor' named entity 'EGFR' named entity 'apoptosis' named entity 'bacteria' named entity 'HPV' named entity 'pathogen' named entity 'oncogenesis' named entity 'constitutively active' named entity 'tight-junction' named entity 'cell death' named entity 'downregulation' named entity 'virus' named entity 'AREG' named entity 'infection' named entity 'ErbB' named entity 'infection' named entity 'signalling pathways' named entity 'pathogens' named entity 'cell survival' named entity 'EBV' named entity 'type 16' named entity 'EGFR' named entity 'EGFR' named entity 'junction proteins' named entity 'hemagglutinin' named entity 'mucous gland' named entity 'by-product' named entity 'microbes' named entity 'protein' named entity 'Mahvash' named entity 'ErbB' named entity 'kinase inhibitor' named entity 'mRNA' named entity 'signalling pathways' named entity 'Erk2' named entity 'ErbB3' named entity 'EGFR' named entity 'siRNAs' named entity 'S100A10' named entity 'lipid' named entity 'cellular transformation' named entity 'EGFR' named entity 'upregulation' named entity 'JNK activation' named entity 'host immunity' named entity 'EGFR' named entity 'CD81' named entity 'cell death' named entity 'lung function' named entity 'pathogen' named entity 'Campylobacter jejuni' named entity 'Mcl-1' named entity 'pathogens' named entity 'signalling molecules' named entity 'epithelial cells' named entity 'fibrosis'

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