About: The 2019‐new coronavirus epidemic: Evidence for virus evolution

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: The 2019‐new coronavirus epidemic: Evidence for virus evolution Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	The 2019‐new coronavirus epidemic: Evidence for virus evolution
Creator	Angeletti, Silvia Benvenuto, Domenico Ciccozzi, Massimo Giovanetti, Marta Ciccozzi, Alessandra Angeletti, Cruz, Oswaldo Rome, Bio-Medico, Campus Correspondence, Silvia Cruz, Rio De Janeiro, Rome, Italy Spoto, \|
source	Medline; PMC
abstract	There is a worldwide concern about the new coronavirus 2019‐nCoV as a global public health threat. In this article, we provide a preliminary evolutionary and molecular epidemiological analysis of this new virus. A phylogenetic tree has been built using the 15 available whole genome sequences of 2019‐nCoV, 12 whole genome sequences of 2019‐nCoV, and 12 highly similar whole genome sequences available in gene bank (five from the severe acute respiratory syndrome, two from Middle East respiratory syndrome, and five from bat SARS‐like coronavirus). Fast unconstrained Bayesian approximation analysis shows that the nucleocapsid and the spike glycoprotein have some sites under positive pressure, whereas homology modeling revealed some molecular and structural differences between the viruses. The phylogenetic tree showed that 2019‐nCoV significantly clustered with bat SARS‐like coronavirus sequence isolated in 2015, whereas structural analysis revealed mutation in Spike Glycoprotein and nucleocapsid protein. From these results, the new 2019‐nCoV is distinct from SARS virus, probably trasmitted from bats after mutation conferring ability to infect humans.
has issue date	2020-02-07(xsd:dateTime)
bibo:doi	10.1002/jmv.25688
bibo:pmid	31994738
has license	no-cc
sha1sum (hex)	7142ff45dbca092b80f3e5eaf6da6d4f4b42e03a
schema:url	https://doi.org/10.1002/jmv.25688
resource representing a document's title	The 2019‐new coronavirus epidemic: Evidence for virus evolution
has PubMed Central identifier	PMC7166400
has PubMed identifier	31994738
schema:publication	J Med Virol
resource representing a document's body	covid:7142ff45dbca092b80f3e5eaf6da6d4f4b42e03a#body_text
is schema:about of	named entity 'homology modeling' named entity 'provide' named entity 'severe acute respiratory syndrome' named entity '2019-nCoV' named entity 'molecular' named entity 'Middle East respiratory syndrome' named entity 'bat' named entity 'Middle East respiratory syndrome' named entity 'homology modeling' named entity 'nCoV' named entity 'coronavirus 2019' named entity 'severe acute respiratory syndrome' named entity 'phylogenetic tree' named entity 'global public health' named entity 'virus' named entity 'gene bank' named entity '2019-nCoV' named entity 'coronavirus epidemic' named entity 'virus evolution' named entity 'gamma distribution' named entity '2019-nCoV' named entity 'phylogenetic' named entity 'common cold' named entity 'diversifying selection' named entity 'basic local alignment search tool' named entity 'genome sequences' named entity 'MERS' named entity 'phylogenetic tree' named entity 'selection pressure' named entity 'SARS' named entity 'Three-dimensional structures' named entity 'Homology models' named entity 'genomes' named entity 'virus' named entity 'multiple sequence alignment' named entity '2019-nCoV' named entity 'ncbi.nlm.nih.gov' named entity 'bat' named entity 'adaptive evolution' named entity 'RNA viruses' named entity 'HHPred' named entity 'bat' named entity 'probability' named entity 'phylogenetic tree' named entity 'PyMOL' named entity 'statistically significant' named entity 'Middle East respiratory syndrome' named entity 'likelihood ratio test' named entity '2019-nCoV' named entity 'evolution' named entity 'vaccine' named entity 'phylogenetic tree' named entity 'nested models' named entity 'SARS' named entity 'GISAID' named entity 'FUBAR' named entity 'Coronaviridae' named entity 'substitution model' named entity 'GenBank' named entity 'SARS-like coronavirus' named entity 'genome sequences' named entity 'SARS-like coronavirus' named entity 'glycoprotein' named entity 'Fast' named entity 'GLOBAL' named entity 'WHOLE GENOME' named entity 'ARTICLE' named entity 'PRELIMINARY'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software