About: Full-Length Genomic Analysis of Korean Porcine Sapelovirus Strains

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Full-Length Genomic Analysis of Korean Porcine Sapelovirus Strains
Creator	Choi, J Kang, J-S Kim, K-Y Kwon, D-S
Source	PMC
abstract	Porcine sapelovirus (PSV), a species of the genus Sapelovirus within the family Picornaviridae, is associated with diarrhea, pneumonia, severe neurological disorders, and reproductive failure in pigs. However, the structural features of the complete PSV genome remain largely unknown. To analyze the structural features of PSV genomes, the full-length nucleotide sequences of three Korean PSV strains were determined and analyzed using bioinformatic techniques in comparison with other known PSV strains. The Korean PSV genomes ranged from 7,542 to 7,566 nucleotides excluding the 3′ poly(A) tail, and showed the typical picornavirus genome organization; 5′untranslated region (UTR)-L-VP4-VP2-VP3-VP1-2A-2B-2C-3A-3B-3C-3D-3′UTR. Three distinct cis-active RNA elements, the internal ribosome entry site (IRES) in the 5′UTR, a cis-replication element (CRE) in the 2C coding region and 3′UTR were identified and their structures were predicted. Interestingly, the structural features of the CRE and 3′UTR were different between PSV strains. The availability of these first complete genome sequences for PSV strains will facilitate future investigations of the molecular pathogenesis and evolutionary characteristics of PSV.
has issue date	2014-09-17(xsd:dateTime)
bibo:doi	10.1371/journal.pone.0107860
bibo:pmid	25229940
has license	cc-by
sha1sum (hex)	6e400ccc14e21a503c93f6ef8518d9b0d2d6faf3
schema:url	https://doi.org/10.1371/journal.pone.0107860
resource representing a document's title	Full-Length Genomic Analysis of Korean Porcine Sapelovirus Strains
has PubMed Central identifier	PMC4168140
has PubMed identifier	25229940
schema:publication	PLoS One
resource representing a document's body	covid:6e400ccc14e21a503c93f6ef8518d9b0d2d6faf3#body_text
is schema:about of	named entity 'picornavirus' named entity 'genomes' named entity 'remain' named entity 'ASSOCIATED WITH' named entity 'CHARACTERISTICS' named entity 'GENUS SAPELOVIRUS' named entity 'THEIR' named entity 'PSV' named entity 'coding region' named entity 'neurological disorders' named entity 'Korean' named entity 'UTR' named entity 'PSV' named entity 'Three' named entity 'bioinformatic' named entity 'Analysis' named entity 'Porcine' named entity 'cis' named entity 'PSV' named entity 'picornavirus' named entity 'PSV' named entity 'genomes' named entity 'genomes' named entity 'PSV' named entity 'cis' named entity 'nucleotide sequences' named entity 'genome sequences' named entity 'internal ribosome entry site' named entity 'nucleotides' named entity 'RNA elements' named entity 'PSV' named entity 'Porcine' named entity 'coding region' named entity 'Teschovirus' named entity 'transmission electron microscopy' named entity 'eIF' named entity 'RNA' named entity 'stem-loop structures' named entity 'cleavage' named entity 'PSV' named entity 'Avihepatovirus' named entity 'GenBank' named entity 'confocal scanning' named entity 'VPg' named entity 'picornaviruses' named entity 'RNA replication' named entity 'polyprotein' named entity 'PSV' named entity 'primer pairs' named entity 'poly(A) tail' named entity 'Picornaviruses' named entity 'PCR' named entity 'nucleotides' named entity 'nucleotides' named entity 'VPg' named entity 'Primer' named entity 'RNA' named entity 'ORF' named entity 'PBS' named entity 'Seoul' named entity 'PSV' named entity 'GenBank' named entity 'RNA' named entity 'Enterovirus' named entity 'coding sequence' named entity 'phylogenetically' named entity 'capsid' named entity 'IRES' named entity 'picornaviruses' named entity 'antibiotics' named entity 'cDNA' named entity 'epidemiological study' named entity 'RNA' named entity 'Erbovirus' named entity 'South Korea' named entity 'cis' named entity 'RNA' named entity 'zinc-finger'

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