About: Sex differences underlying preexisting cardiovascular disease and cardiovascular injury in COVID-19

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About: Sex differences underlying preexisting cardiovascular disease and cardiovascular injury in COVID-19 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Sex differences underlying preexisting cardiovascular disease and cardiovascular injury in COVID-19
Creator	Li, Min Geffen, David Hong, Jason Amjedi, Marjan Cunningham Bsc, Christine Cunningham, Christine Eghbali, Mansoureh Medzikovic, Lejla Ruffenach, Gregoire
Source	Elsevier; Medline; PMC
abstract	The novel 2019 coronavirus disease (COVID-19), resulting from severe acute respiratory syndrome coronarvirus-2 (SARS-CoV-2) infection, typically leads to respiratory failure in severe cases; however, cardiovascular injury is reported to contribute to a substantial proportion of COVID-19 deaths. Preexisting cardiovascular disease (CVD) is among the most common risk factors for hospitalization and death in COVID-19 patients, and the pathogenic mechanisms of COVID-19 disease progression itself may promote the development of cardiovascular injury, increasing risk of in-hospital death. Sex differences in COVID-19 are becoming more apparent as mounting data indicate that males seem to be disproportionately at risk of severe COVID-19 outcome due to preexisting CVD and COVID-19-related cardiovascular injury. In this review, we will provide a basic science perspective on current clinical observations in this rapidly evolving field and discuss the interplay sex differences, preexisting CVD and COVID-19-related cardiac injury.
has issue date	2020-08-22(xsd:dateTime)
bibo:doi	10.1016/j.yjmcc.2020.08.007
bibo:pmid	32835666
has license	no-cc
sha1sum (hex)	6a4547c4792c9cbe7b0fb7fd849c0edc1550514c
schema:url	https://doi.org/10.1016/j.yjmcc.2020.08.007
resource representing a document's title	Sex differences underlying preexisting cardiovascular disease and cardiovascular injury in COVID-19
has PubMed Central identifier	PMC7442559
has PubMed identifier	32835666
schema:publication	J Mol Cell Cardiol
resource representing a document's body	covid:6a4547c4792c9cbe7b0fb7fd849c0edc1550514c#body_text
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