About: Electron microscopy: essentials for viral structure, morphogenesis and rapid diagnosis

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Electron microscopy: essentials for viral structure, morphogenesis and rapid diagnosis
Creator	Zhang, Ying Song, Jingdong Jinsheng, Tao, Hung
Source	Medline; PMC
abstract	Electron microscopy (EM) should be used in the front line for detection of agents in emergencies and bioterrorism, on accounts of its speed and accuracy. However, the number of EM diagnostic laboratories has decreased considerably and an increasing number of people encounter difficulties with EM results. Therefore, the research on viral structure and morphologyant in EM diagnostic practice. EM has several technological advantages, and should be a fundamental tool in clinical diagnosis of viruses, particularly when agents are unknown or unsuspected. In this article, we review the historical contribution of EM to virology, and its use in virus differentiation, localization of specific virus antigens, virus-cell interaction, and viral morphogenesis. It is essential that EM investigations are based on clinical and comprehensive pathogenesis data from light or confocal microscopy. Furthermore, avoidance of artifacts or false results is necessary to exploit fully the advantages while minimizing its limitations.
has issue date	2013-05-01(xsd:dateTime)
bibo:doi	10.1007/s11427-013-4476-2
bibo:pmid	23633074
has license	cc-by
sha1sum (hex)	6810812121d66ad44b45c388c3744a4b5f3bb001
schema:url	https://doi.org/10.1007/s11427-013-4476-2
resource representing a document's title	Electron microscopy: essentials for viral structure, morphogenesis and rapid diagnosis
has PubMed Central identifier	PMC7089233
has PubMed identifier	23633074
schema:publication	Sci China Life Sci
resource representing a document's body	covid:6810812121d66ad44b45c388c3744a4b5f3bb001#body_text
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