About: The impact of tracheostomy timing on clinical outcomes and adverse events in intubated patients with infratentorial lesions: early versus late tracheostomy

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About: The impact of tracheostomy timing on clinical outcomes and adverse events in intubated patients with infratentorial lesions: early versus late tracheostomy Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The impact of tracheostomy timing on clinical outcomes and adverse events in intubated patients with infratentorial lesions: early versus late tracheostomy
Creator	Wu, Zhen Xu, Ming Chen, Guang-Qiang Huang, Hua-Wei Zhang, Guo-Bin Zhang, Jun-Ting Zhang, Xiao-Kang Zhou, Jian-Xin
Source	PMC
abstract	We evaluated the association between the timing of tracheostomy and clinical outcomes in patients with infratentorial lesions. We performed a retrospective observational cohort study in a neurosurgical intensive care unit (ICU) at a tertiary academic medical center from January 2014 to December 2018. Consecutive adult patients admitted to the ICU who underwent resection of infratentorial lesions as well as tracheostomy were included for analysis. Early tracheostomy was defined as performed on postoperative days 1–10 and late tracheostomy on days 10–20 after operation. Univariate and multivariate analyses were used to compare the characteristics and outcomes between both cohorts. A total of 143 patients were identified, and 96 patients received early tracheostomy. Multivariable analysis identified early tracheostomy as an independent variable associated with lower occurrence of pneumonia (odds ratio, 0.25; 95% CI, 0.09–0.73; p = 0.011), shorter stays in ICUs (hazard ratio, 0.4; 95% CI, 0.3–0.6; p = 0.03), and earlier decannulation (hazard ratio, 0.5; 95% CI, 0.4–0.8; p = 0.003). However, no significant differences were observed between the early and late tracheostomy groups regarding hospital mortality (p > 0.999) and the modified Rankin scale after 6 months (p = 0.543). We also identified postoperative brainstem deficits, including cough, swallowing attempts, and extended tongue as well as GCS < 8 at ICU admission as the risk factors independently associated with patients underwent tracheostomy. There is a significant association between early tracheostomy and beneficial clinical outcomes or reduced adverse event occurrence in patients with infratentorial lesions. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10143-020-01339-7) contains supplementary material, which is available to authorized users.
has issue date	2020-06-25(xsd:dateTime)
bibo:doi	10.1007/s10143-020-01339-7
has license	no-cc
sha1sum (hex)	672c21cd0847a250a131adcf0bfdf7ccd11e1938
schema:url	https://doi.org/10.1007/s10143-020-01339-7
resource representing a document's title	The impact of tracheostomy timing on clinical outcomes and adverse events in intubated patients with infratentorial lesions: early versus late tracheostomy
has PubMed Central identifier	PMC7314615
schema:publication	Neurosurg Rev
resource representing a document's body	covid:672c21cd0847a250a131adcf0bfdf7ccd11e1938#body_text
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