About: The effect of dietary intake of the acidic protein fraction of bovine colostrum on influenza A (H1N1) virus infection

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About: The effect of dietary intake of the acidic protein fraction of bovine colostrum on influenza A (H1N1) virus infection Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The effect of dietary intake of the acidic protein fraction of bovine colostrum on influenza A (H1N1) virus infection
Creator	Kim, Hong-Jin Kim, Jin Chang, Yong Xu, Mei
Source	Medline; PMC
abstract	Acidic protein levels in the milk decrease markedly as lactation progresses, suggesting that it is an important part of the colostrum. However, little attention has been paid to their biological function. In this study, we isolated the acidic protein fraction of bovine colostrum (AFC, isoelectric point <5) by anion-exchange chromatography, and investigated the effect of its dietary intake on influenza A (H1N1) virus infection. 100% of mice infected with 1 LD(50) of the virus survived when administered AFC for 14 days prior to infection, compared with 33% survival when administered phosphate buffered saline (PBS). Moreover, consumption of AFC reduced the weight loss associated with infection. We propose that dietary intake of AFC has a prophylactic effect on influenza A virus infection. ELECTRONIC SUPPLEMENTARY MATERIAL: Supplementary material is available for this article at 10.1007/s12275-013-2683-y and is accessible for authorized users.
has issue date	2013-04-26(xsd:dateTime)
bibo:doi	10.1007/s12275-013-2683-y
bibo:pmid	23620352
has license	no-cc
sha1sum (hex)	66f332afb3cfd68bcacc440946484860f418bf46
schema:url	https://doi.org/10.1007/s12275-013-2683-y
resource representing a document's title	The effect of dietary intake of the acidic protein fraction of bovine colostrum on influenza A (H1N1) virus infection
has PubMed Central identifier	PMC7090844
has PubMed identifier	23620352
schema:publication	J Microbiol
resource representing a document's body	covid:66f332afb3cfd68bcacc440946484860f418bf46#body_text
is schema:about of	named entity 'PBS' named entity 'infection' named entity 'Fraction' named entity 'Colostrum' named entity 'LACTATION' named entity 'ITS' named entity 'isoelectric point' named entity 'weight loss' named entity 'biological function' named entity 'protein' named entity 'AFC' named entity 'colostrum' named entity 'protein' named entity 'anion-exchange chromatography' named entity 'influenza A virus' named entity 'infection' named entity 'prophylactic' named entity 'virus' named entity 'Bovine' named entity 'protein' named entity 'LD50' named entity 'bovine' named entity 'NaCl' named entity 'colostrum' named entity 'colostrum' named entity 'Bio-Rad' named entity 'bovine' named entity 'influenza' named entity 'dietary intake' named entity 'Student's t-test' named entity 'infection' named entity 'colostrum' named entity 'centrifuged' named entity 'colostrum' named entity 'high-quality' named entity 'Breast milk' named entity 'developed countries' named entity 'virus' named entity 'influenza virus' named entity 'virus' named entity 'epidemics' named entity 'allantoic' named entity 'oseltamivir' named entity 'influenza A virus' named entity 'oligosaccharide' named entity 'protein' named entity 'LD 50' named entity 'influenza' named entity 'influenza infection' named entity 'mice' named entity 'mice' named entity 'PBS' named entity 'LD50' named entity 'influenza' named entity 'protein' named entity 'sialic acid' named entity 'protein' named entity 'oseltamivir' named entity 'pathogens' named entity 'bovine' named entity 'infection' named entity 'morbidity' named entity 'infection' named entity 'protein' named entity 'colostrum' named entity 'influenza virus' named entity 'PBS' named entity 'oseltamivir' named entity 'bovine' named entity 'virus' named entity 'pathogens' named entity 'Survival rates' named entity 'colostrum' named entity 'PBS' named entity 'Bio-Rad' named entity 'protein' named entity 'LD50' named entity 'colostrum'

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