About: Asymptomatic SARS-CoV-2 infection and COVID-19 mortality during an outbreak investigation in a skilled nursing facility

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About: Asymptomatic SARS-CoV-2 infection and COVID-19 mortality during an outbreak investigation in a skilled nursing facility Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Asymptomatic SARS-CoV-2 infection and COVID-19 mortality during an outbreak investigation in a skilled nursing facility
Creator	Chugh, Rashmi Bleasdale, Susan Burdsall, Deborah Ezike, Ngozi Murphy, Elizabeth Akker, Lynn Borgetti, Scott Bryars, Debra Chaisson, Lelia Hoff, Christopher Murskyj, Emily Patel, Mahesh Ramos, Joe Thomas-Smith, Evonda Wilson, Shannon
Source	Medline; PMC
abstract	BACKGROUND: Outbreaks of COVID-19 have been reported in nursing homes and assisted living facilities; however, the extent of asymptomatic and pre-symptomatic SARS-CoV-2 infection in this high-risk population remains unclear. METHODS: We conducted an investigation of the first known outbreak of SARS-CoV-2 at a skilled nursing facility (SNF) in Illinois on March 15, 2020 and followed residents for 30 days. We tested 126/127 residents for SARS-CoV-2 via RT-PCR and performed symptom assessments. We calculated the point prevalence of SARS-CoV-2 and assessed symptom onset over 30-day follow-up to determine: 1) the proportion of cases who were symptomatic, pre-symptomatic, and asymptomatic and 2) incidence of symptoms among those who tested negative. We used the Kaplan-Meier method to determine the 30-day probability of death for cases. RESULTS: Of 126 residents tested, 33 had confirmed SARS-CoV-2 on March 15. Nineteen (58%) had symptoms at the time of testing, 1 (3%) developed symptoms over follow-up, and 13 (39%) remained asymptomatic. Thirty-five residents who tested negative on March 15 developed symptoms over follow-up; of these, 3 were re-tested and 2 were positive. The 30-day probability of death among cases was 29%. CONCLUSIONS: SNFs are particularly vulnerable to SARS-CoV-2, and residents are at risk of severe outcomes. Attention must be paid to preventing outbreaks in these and other congregate care settings. Widespread testing and infection control are key to help prevent COVID-19 morbidity and mortality in these high-risk populations.
has issue date	2020-06-16(xsd:dateTime)
bibo:doi	10.1093/cid/ciaa763
bibo:pmid	32548628
has license	no-cc
sha1sum (hex)	5fdcaeccb4a9069699dc66016fee8757239c6d2b
schema:url	https://doi.org/10.1093/cid/ciaa763
resource representing a document's title	Asymptomatic SARS-CoV-2 infection and COVID-19 mortality during an outbreak investigation in a skilled nursing facility
has PubMed Central identifier	PMC7337684
has PubMed identifier	32548628
schema:publication	Clin Infect Dis
resource representing a document's body	covid:5fdcaeccb4a9069699dc66016fee8757239c6d2b#body_text
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