About: Targeting viral entry as a strategy for broad-spectrum antivirals

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Targeting viral entry as a strategy for broad-spectrum antivirals
Creator	Wang, Jun Marsh, Mark Mazzon, Michela California, Simmons Francisco, Graham Usa,
Source	Medline; PMC
abstract	The process of entry into a host cell is a key step in the life cycle of most viruses. In recent years, there has been a significant increase in our understanding of the routes and mechanisms of entry for a number of these viruses. This has led to the development of novel broad-spectrum antiviral approaches that target host cell proteins and pathways, in addition to strategies focused on individual viruses or virus families. Here we consider a number of these approaches and their broad-spectrum potential.
has issue date	2019-09-12(xsd:dateTime)
bibo:doi	10.12688/f1000research.19694.1
bibo:pmid	31559009
has license	cc-by
sha1sum (hex)	5aebac2302d94acc406291d65cc7c538ab71dae1
schema:url	https://doi.org/10.12688/f1000research.19694.1
resource representing a document's title	Targeting viral entry as a strategy for broad-spectrum antivirals
has PubMed Central identifier	PMC6743247
has PubMed identifier	31559009
schema:publication	F1000Res
resource representing a document's body	covid:5aebac2302d94acc406291d65cc7c538ab71dae1#body_text
is schema:about of	named entity 'Peer Review' named entity 'Targeting' named entity 'peer review' named entity 'BROAD' named entity 'REVIEWS' named entity 'APPROVED' named entity 'OPEN' named entity 'FACULTY' named entity 'PUBLICATION' named entity 'WRITTEN' named entity 'FINAL' named entity 'SPECTRUM' named entity 'APPROVED' named entity 'VIRAL ENTRY' named entity 'ANTIVIRALS' named entity 'STRATEGY' named entity 'MEMBERS' named entity 'THEIR' named entity 'VERSION' named entity 'COMPREHENSIVE' named entity 'PUBLISHED' named entity 'PEER REVIEW' named entity 'NAMES' named entity 'PEER REVIEWED' named entity 'AFFILIATIONS' named entity 'TARGETING' named entity 'ENSURE' named entity 'ACCESSIBLE' named entity 'F1000' named entity 'broad-spectrum' named entity 'F1000' named entity 'Open Peer Review' named entity 'niclosamide' named entity 'viral proteins' named entity 'cytoplasm' named entity 'viral resistance' named entity 'polysaccharides' named entity 'chronic infection' named entity 'virus replication' named entity 'neonatal' named entity 'cellular pathways' named entity 'epidermal growth factor receptors' named entity 'dendrimers' named entity 'virus' named entity 'virus' named entity 'Tyrphostin' named entity 'EBOV' named entity 'late endosomes' named entity 'small-molecule' named entity 'orthomyxoviruses' named entity 'SARS' named entity 'virus infection' named entity 'antiviral' named entity 'human papilloma virus' named entity 'endocytosis' named entity 'MERS' named entity 'glycolipids' named entity 'A71' named entity 'pathogenesis' named entity 'CCR5' named entity 'CD4' named entity 'placental development' named entity 'virus infection' named entity 'infection' named entity 'potassium' named entity 'syncytin' named entity 'genome' named entity 'Wec' named entity 'cellular metabolism' named entity 'virus' named entity 'Antibody' named entity 'p21' named entity 'virion' named entity 'non-specific' named entity 'intracellular compartments' named entity 'maraviroc'

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