About: From SARS to MERS: evidence and speculation

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	From SARS to MERS: evidence and speculation
Creator	Gao, Hainv Li, Lanjuan Yang, Shigui Yao, Hangping
Source	Medline; PMC
abstract	The Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel zoonotic pathogen. In 2012, the infectious outbreak caused by MERS-CoV in Saudi Arabia has spread to more than 1600 patients in 26 countries, resulting in over 600 deaths.Without a travel history, few clinical and radiological features can reliably differentiate MERS from SARS. But in real world, comparing with SARS, MERS presents more vaguely defined epidemiology, more severe symptoms, and higher case fatality rate. In this review, we summarize the recent findings in the field of MERS-CoV, especially its molecular virology, interspecies mechanisms, clinical features, antiviral therapies, and the further investigation into this disease. As a newly emerging virus, many questions are not fully answered, including the exact mode of transmission chain, geographical distribution, and animal origins. Furthermore, a new protocol needs to be launched to rapidly evaluate the effects of unproven antiviral drugs and vaccine to fasten the clinical application of new drugs.
has issue date	2016-12-23(xsd:dateTime)
bibo:doi	10.1007/s11684-016-0466-7
bibo:pmid	27726088
has license	no-cc
sha1sum (hex)	53bc05147511693d56aa5cfe1ba38931da0a7ecb
schema:url	https://doi.org/10.1007/s11684-016-0466-7
resource representing a document's title	From SARS to MERS: evidence and speculation
has PubMed Central identifier	PMC7088694
has PubMed identifier	27726088
schema:publication	Front Med
resource representing a document's body	covid:53bc05147511693d56aa5cfe1ba38931da0a7ecb#body_text
is schema:about of	named entity 'MERS' named entity 'MERS-COV' named entity 'EVIDENCE' named entity 'RAPIDLY' named entity 'FULLY' named entity 'SPECULATION' named entity 'CLINICAL' named entity 'SARS' named entity 'BUT' named entity 'COMPARING' named entity 'REAL' named entity 'INVESTIGATION' named entity 'CLINICAL FEATURES' named entity 'REVIEW' named entity 'CHAIN' named entity 'VIRUS' named entity '1600' named entity 'PATIENTS' named entity 'EXACT' named entity 'DIFFERENTIATE' named entity 'MECHANISMS' named entity 'PRESENTS' named entity 'MODE OF TRANSMISSION' named entity 'NEWLY' named entity 'ITS' named entity 'FASTEN' named entity 'INFECTIOUS' named entity 'MORE THAN' named entity 'INCLUDING' named entity 'CLINICAL APPLICATION' named entity 'IS A' named entity 'DEFINED' named entity 'CAUSED BY' named entity 'SARS' named entity 'MERS' named entity 'MERS' named entity 'ANTIVIRAL DRUGS' named entity 'RESULTING IN' named entity 'CASE FATALITY RATE' named entity 'VACCINE' named entity 'EPIDEMIOLOGY' named entity 'FEATURES' named entity 'DEATHS' named entity 'GEOGRAPHICAL DISTRIBUTION' named entity 'OUTBREAK' named entity 'ANIMAL' named entity 'ANTIVIRAL' named entity 'MOLECULAR VIROLOGY' named entity 'EVALUATE' named entity 'EFFECTS' named entity 'PROTOCOL' named entity 'ZOONOTIC PATHOGEN' named entity 'COUNTRIES' named entity 'IN THE FIELD' named entity 'DISEASE' named entity 'NOVEL' named entity 'ORIGINS' named entity 'THERAPIES' named entity 'DRUGS' named entity 'SAUDI ARABIA' named entity 'HIGHER' named entity 'SPREAD' named entity 'RECENT' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'NEEDS' named entity 'FINDINGS' named entity 'UNPROVEN' named entity 'WORLD' named entity 'SEVERE SYMPTOMS' named entity '600' named entity 'NEW' covid:arg/53bc05147511693d56aa5cfe1ba38931da0a7ecb named entity 'patients' named entity 'investigation' named entity 'mechanisms' named entity 'emerging' named entity 'transmission' named entity 'rapidly'

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