About: Respiratory-syncytial-virus- and rhinovirus-related bronchiolitis in children aged <2 years in an English district general hospital

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About: Respiratory-syncytial-virus- and rhinovirus-related bronchiolitis in children aged <2 years in an English district general hospital Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Respiratory-syncytial-virus- and rhinovirus-related bronchiolitis in children aged <2 years in an English district general hospital
Creator	Turner, P Clayton, B Harvey, M Mcallister, T Mukherjee, A Paul, S
Source	Elsevier; Medline; PMC
abstract	Summary Background Bronchiolitis is the most common reason for hospitalization in young children. In addition to respiratory syncytial virus (RSV), other viruses have been increasingly implicated. Guidance on testing has also changed. Aims To compare clinicopathological outcomes in young children admitted with bronchiolitis due to RSV in comparison with rhinovirus (RV), and identify associated risk/epidemiological factors. Methods Children aged less than two years admitted to hospital with a clinical diagnosis of bronchiolitis with positive results for either RSV or RV were included in this study. Polymerase-chain-reaction-negative cases using an extended respiratory virus panel served as a control group. Retrospective data were collected on sex, risk factors, respiratory support, intravenous fluids and antibiotics. Outcomes such as length of stay (LOS) and need for transfer to the high-dependency unit/paediatric intensive care unit were included. Findings Two hundred and twenty-seven out of 437 nasopharyngeal aspirate samples were positive for either RSV (N = 162) or RV (N = 65). The median age of cases was three months and 75% had at least one risk factor. Risk factors were higher in the RV group (P = 0.004). RV accounted for the majority of cases outside the RSV season (P < 0.01). RV-associated bronchiolitis had a longer LOS (more than seven days) (P < 0.05) and increased need for chest X-rays and/or antibiotics (P < 0.05). Use of intravenous fluids and respiratory support were higher in the RV group, but the difference was not significant. Conclusions RV is the second most common pathogen associated with bronchiolitis and is isolated all year round. This may be important in those with risk factors resulting in prolonged LOS. Further research is necessary to establish the exact role of RV in this common condition, particularly outside the traditional RSV season.
has issue date	2017-08-31(xsd:dateTime)
bibo:doi	10.1016/j.jhin.2017.04.023
bibo:pmid	28559125
has license	els-covid
sha1sum (hex)	50155b067f389bd8713b41fcc77ab4fe6b3039a4
schema:url	https://doi.org/10.1016/j.jhin.2017.04.023
resource representing a document's title	Respiratory-syncytial-virus- and rhinovirus-related bronchiolitis in children aged <2 years in an English district general hospital
has PubMed Central identifier	PMC7114599
has PubMed identifier	28559125
schema:publication	Journal of Hospital Infection
resource representing a document's body	covid:50155b067f389bd8713b41fcc77ab4fe6b3039a4#body_text
is schema:about of	named entity 'AGED' named entity 'bronchiolitis' named entity 'BRONCHIOLITIS' named entity 'RESPIRATORY' named entity 'RESPIRATORY SYNCYTIAL VIRUS' covid:arg/50155b067f389bd8713b41fcc77ab4fe6b3039a4 named entity 'RESPIRATORY' named entity 'BRONCHIOLITIS' named entity 'DISTRICT' named entity 'GENERAL HOSPITAL' named entity 'VIRUS' named entity 'RHINOVIRUS' named entity 'SYNCYTIAL' named entity 'ENGLISH' named entity 'RELATED' named entity 'YEARS' named entity 'CHILDREN' named entity 'PCR' named entity 'NASOPHARYNGEAL ASPIRATE' named entity 'Nasopharyngeal aspirate' named entity 'infection' named entity 'risk factors' named entity 'oxygen' named entity 'bronchiolitis' named entity 'pathogen' named entity 'RSV' named entity 'RSV' named entity 'RSV' named entity 'oxygen' named entity 'AAP' named entity 'neonatal units' named entity 'chest X-ray' named entity 'RSV' named entity 'chest X-ray' named entity 'RSV' named entity 'fever' named entity 'viral pathogen' named entity 'bronchiolitis' named entity 'pathogens' named entity 'polymerase chain reaction' named entity 'RSV' named entity 'human metapneumovirus' named entity 'RSV' named entity 'antibiotics' named entity 'infection' named entity 'virus' named entity '0.01' named entity 'virus' named entity 'human metapneumovirus' named entity 'bronchiolitis' named entity '21 days' named entity 'pathogens' named entity 'common colds' named entity 'pathogens' named entity 'HDU' named entity 'coinfection' named entity 'RSV' named entity 'RSV' named entity 'antibiotic treatment' named entity 'microbiology' named entity 'bronchiolitis' named entity 'antigen' named entity 'RSV' named entity 'RSV' named entity 'viruses' named entity 'bronchiolitis' named entity 'antibiotic' named entity 'hospital settings' named entity 'nosocomially' named entity 'temperate climates' named entity 'RSV' named entity 'RSV' named entity '0.01' named entity 'RSV' named entity 'viral pathogens' named entity 'antibiotics'

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