About: Porcine deltacoronavirus infection alters bacterial communities in the colon and feces of neonatal piglets

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Porcine deltacoronavirus infection alters bacterial communities in the colon and feces of neonatal piglets Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Porcine deltacoronavirus infection alters bacterial communities in the colon and feces of neonatal piglets
Source	Medline; PMC
abstract	Porcine deltacoronavirus (PDCoV) is a novel enteropathogenic coronavirus that causes watery diarrhea in piglets. Little is known regarding the alteration of the gut microbiota in PDCoV‐induced diarrhea piglets. In this study, 5‐day‐old piglets were experimentally infected with PDCoV strain CH‐01, and all piglets developed typical clinical disease, characterized by acute and severe watery diarrhea. Histologic lesions were limited to the villous epithelium of the duodenum and ileum. Gut microbiota profiles in the colon and feces of piglets inoculated with PDCoV were investigated using 16S rRNA sequencing. The results showed that PDCoV infection reduced bacterial diversity and significantly altered the composition of the microbiota from the phylum to the genus level in the colon and feces of piglets. Firmicutes (phylum), Lactobacillaceae (family), and Lactobacillus (genus) were significantly increased (p < .01), while the abundance of Bacteroidetes (phylum) was markedly reduced in the colon and feces of the PDCoV‐infected piglets (p < .01) when compared to those of the healthy piglets. Furthermore, microbial function prediction indicated that the changes in the intestinal flora also affected the nucleotide transport and metabolism, defense, translation, and transcription function of the intestinal microbiota. The current study provides new insight into the pathology and physiology of PDCoV.
has issue date	2020-04-01(xsd:dateTime)
bibo:doi	10.1002/mbo3.1036
bibo:pmid	32239666
has license	cc-by-nc-nd
sha1sum (hex)	4fc1d8b553b16075958d57a3375cf4790c5a4dfd
schema:url	https://doi.org/10.1002/mbo3.1036
resource representing a document's title	Porcine deltacoronavirus infection alters bacterial communities in the colon and feces of neonatal piglets
has PubMed Central identifier	PMC7349149
has PubMed identifier	32239666
schema:publication	Microbiologyopen
resource representing a document's body	covid:4fc1d8b553b16075958d57a3375cf4790c5a4dfd#body_text
is schema:about of	named entity 'diarrhea' named entity 'small intestines' named entity 'RNA' named entity 'vaccines' named entity 'Henan Province' named entity 'amino acid metabolism' named entity 'PEDV' named entity 'pathogenic bacteria' named entity 'Diarrhea' named entity 'infection' named entity 'Reverse Transcription' named entity 'CI group' named entity 'CI group' named entity 'RNA' named entity 'MEM' named entity 'qRT-PCR' named entity 'multiple testing' named entity 'atrophic' named entity 'Bacteroidetes' named entity 'minimum essential medium' named entity 'GenBank' named entity 'intestinal content' named entity 'dysbiosis' named entity 'carbohydrate' named entity 'virus' named entity 'microbial' named entity 'watery diarrhea' named entity 'qRT-PCR' named entity 'clinical signs' named entity 'piglet' named entity 'control group' named entity 'ileum' named entity 'diarrhea' named entity 'virus' named entity 'microbiota' named entity 'neonatal' named entity 'National Natural Science Foundation' named entity 'feces' named entity 'Piglets' named entity 'fetal bovine serum' named entity 'diarrhea' named entity 'light microscope' named entity 'Firmicutes' named entity 'cecum' named entity 'MEM' named entity 'one-way analysis of variance' named entity 'pig' named entity 'intestinal content' named entity 'Viral' named entity 'PEDV' named entity 'metabolites' named entity 'coronaviruses' named entity 'BIO-RAD' named entity 'microbiota' named entity 'strict anaerobes' named entity 'duodenum' named entity 'dehydration' named entity 'Lactobacillaceae' named entity 'susceptibility to disease' named entity 'PEDV' named entity 'Piglets' named entity 'standard deviation' named entity 'gut microbiota' named entity 'health status' named entity 'control group' named entity 'PCR' named entity 'Coronaviridae' named entity 'immune responses' named entity 'Illumina' named entity 'Porcine deltacoronavirus' named entity 'virus' named entity 'dysbiosis' named entity 'gastrointestinal tract' named entity 'Enterobacteriaceae' named entity 'Bacteroidetes' named entity 'Bacteroidetes' named entity 'OTUs' named entity 'inoculation' named entity 'Viral' named entity 'metabolic' named entity 'MEM' named entity 'intestinal microbiota'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software