About: Spectrum of Cardiac Manifestations in COVID-19: A Systematic Echocardiographic Study

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Spectrum of Cardiac Manifestations in COVID-19: A Systematic Echocardiographic Study
Creator	Amir, Mha Arbel, Yaron Banai, Ariel Baruch, Guy Hochstadt, Aviram Lichter, Yael Merdler, Ilan Oz, Gal Peri, Yogev Rothschild, Ehud Szekely, Yishay Taieb, Philippe Topilsky, Yan
source	Medline; PMC
abstract	Information on the cardiac manifestations of coronavirus disease 2019 (COVID-19) is scarce. We performed a systematic and comprehensive echocardiographic evaluation of consecutive patients hospitalized with COVID-19 infection. METHODS: One hundred consecutive patients diagnosed with COVID-19 infection underwent complete echocardiographic evaluation within 24 hours of admission and were compared with reference values. Echocardiographic studies included left ventricular (LV) systolic and diastolic function and valve hemodynamics and right ventricular (RV) assessment, as well as lung ultrasound. A second examination was performed in case of clinical deterioration. RESULTS: Thirty-two patients (32%) had a normal echocardiogram at baseline. The most common cardiac pathology was RV dilatation and dysfunction (observed in 39% of patients), followed by LV diastolic dysfunction (16%) and LV systolic dysfunction (10%). Patients with elevated troponin (20%) or worse clinical condition did not demonstrate any significant difference in LV systolic function compared with patients with normal troponin or better clinical condition, but they had worse RV function. Clinical deterioration occurred in 20% of patients. In these patients, the most common echocardiographic abnormality at follow-up was RV function deterioration (12 patients), followed by LV systolic and diastolic deterioration (in 5 patients). Femoral deep vein thrombosis was diagnosed in 5 of 12 patients with RV failure. CONCLUSIONS: In COVID-19 infection, LV systolic function is preserved in the majority of patients, but LV diastolic function and RV function are impaired. Elevated troponin and poorer clinical grade are associated with worse RV function. In patients presenting with clinical deterioration at follow-up, acute RV dysfunction, with or without deep vein thrombosis, is more common, but acute LV systolic dysfunction was noted in ≈20%.
has issue date	2020-05-29(xsd:dateTime)
bibo:doi	10.1161/circulationaha.120.047971
bibo:pmid	32469253
has license	no-cc
sha1sum (hex)	4b99ee2f9de7ae4fab678d87b9cc6db1cf272f89
schema:url	https://doi.org/10.1161/circulationaha.120.047971
resource representing a document's title	Spectrum of Cardiac Manifestations in COVID-19: A Systematic Echocardiographic Study
has PubMed Central identifier	PMC7382541
has PubMed identifier	32469253
schema:publication	Circulation
resource representing a document's body	covid:4b99ee2f9de7ae4fab678d87b9cc6db1cf272f89#body_text
is schema:about of	named entity 'lung' named entity 'Electrocardiographic' named entity 'creatinine' named entity 'echocardiographic' named entity 'CRP' named entity 'multiorgan failure' named entity 'infection' named entity 'reference values' named entity 'COVID' named entity 'COVID' named entity 'infection' named entity 'Left ventricular' named entity 'reference values' named entity 'outflow tract' named entity 'pulmonary edema' named entity 'self-limiting' named entity 'infection' named entity 'pathology' named entity 'diastolic' named entity 'oxygen' named entity 'edema' named entity 'pulmonary pressure' named entity 'infection' named entity 'echocardiography' named entity 'Continuing medical education' named entity 'infection' named entity 'hypotension' named entity 'echocardiographic' named entity 'comorbidities' named entity 'peripheral venous thrombosis' named entity 'DVT' named entity 'ultrasound' named entity 'infection' named entity '3.5' named entity 'LVEF' named entity 'troponin' named entity 'COVID' named entity 'ultrasonography' named entity 'Wilcoxon rank-sum test' named entity 'echocardiogram' named entity 'pulmonary vascular resistance' named entity 'heparin' named entity 'hydrostatic' named entity 'computed tomography' named entity 'lung disease' named entity 'MEWS' named entity 'diastolic dysfunction' named entity 'deep vein thrombosis' named entity 'COVID' named entity 'serum lactate' named entity 'CRP' named entity 'infection' named entity 'parenchymal' named entity 'troponin' named entity 'COVID' named entity 'anticoagulant' named entity 'echocardiographic' named entity 'E/A ratio' named entity 'severe infections' named entity 'intensive care' named entity 'mechanical ventilation' named entity 'troponin' named entity 'biomarkers' named entity 'chest pain' named entity 'echocardiographic' named entity 'pleural effusion' named entity 'extracorporeal membrane oxygenation' named entity 'D-dimer' named entity 'COVID-19 infection'

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