About: COVID-19 Outbreak in an Urban Hemodialysis Unit

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	COVID-19 Outbreak in an Urban Hemodialysis Unit
Creator	Muller, Matthew Toronto, Canada Beaubien-Souligny, William Fattouh, Ramzi Lin, Molly Matukas, Larissa Michael's Hospital, St Neskovic, Sanja Shokar, Gagan Siddiqui, Naureen Thomas, Alison Wald, Ron Weinstein, Jordan Yau, Kevin Zaltzman, Jeffrey Jj, Weinstein Lm, Matukas Mp, Muller
Source	Elsevier; Medline; PMC
abstract	RATIONALE & OBJECTIVE: Hemodialysis patients are at increased risk for COVID-19 transmission due, in part, to difficulty maintaining physical distancing. Our hemodialysis unit experienced a COVID-19 outbreak despite following symptom-based screening guidelines. We describe the course of the COVID-19 outbreak and the infection control measures taken for mitigation. STUDY DESIGN: Retrospective cohort study SETTING & PARTICIPANTS: 237 maintenance hemodialysis patients and 93 hemodialysis staff at a single hemodialysis centre in Toronto, Canada. EXPOSURE: Universal screening of patients and staff with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). OUTCOMES: The primary outcome was detection of SARS-CoV-2 in nasopharyngeal samples from patients and staff using reverse transcriptase-polymerase chain reaction (RT-PCR) . ANALYTICAL APPROACH: Descriptive statistics were used for clinical characteristics and the primary outcome. RESULTS: Eleven (4.6%) of 237 hemodialysis patients and 11 of 93 (12%) staff members had a positive RT-PCR test for SARS-CoV-2. Among individuals testing positive, 12 of 22 (55%) were asymptomatic at time of testing, and 7 of 22 (32%) were asymptomatic for the duration of follow-up. One patient was hospitalized at the time of SARS-CoV-2 infection and four additional patients with positive tests were subsequently hospitalized. Two patients (18%) required admission to the intensive care unit. After 30 days follow-up no patients had died or required mechanical ventilation. No hemodialysis staff required hospitalization. Universal droplet and contact precautions were implemented during the outbreak. Hemodialysis staff with SARS-CoV-2 infection were placed on home quarantine regardless of symptom status. Patients with SARS-CoV-2 infection including asymptomatic individuals were treated with droplet and contact precautions until confirmation of negative SARS-CoV-2 RT-PCR testing. Analysis of the outbreak identified two index cases with subsequent nosocomial transmission within the dialysis unit and in shared shuttle buses to the hemodialysis unit. LIMITATIONS: Single centre study. CONCLUSIONS: Universal SARS-CoV-2 testing and universal droplet and contact precautions in the setting of an outbreak appeared to be effective in preventing further transmission.
has issue date	2020-07-15(xsd:dateTime)
bibo:doi	10.1053/j.ajkd.2020.07.001
bibo:pmid	32681983
has license	no-cc
sha1sum (hex)	45752127e66e9670665ad38a324ef491ae15f692
schema:url	https://doi.org/10.1053/j.ajkd.2020.07.001
resource representing a document's title	COVID-19 Outbreak in an Urban Hemodialysis Unit
has PubMed Central identifier	PMC7362862
has PubMed identifier	32681983
schema:publication	Am J Kidney Dis
resource representing a document's body	covid:45752127e66e9670665ad38a324ef491ae15f692#body_text
is schema:about of	named entity 'Journal' named entity 'COVID-19 Outbreak' named entity 'symptom' named entity 'Hemodialysis' named entity 'Assessment Centre' named entity 'severe acute respiratory syndrome coronavirus 2' named entity 'infection control' named entity 'COVID-19' named entity 'hemodialysis' named entity 'COVID-19' named entity 'nasopharyngeal swabs' named entity 'nurse practitioners' named entity 'nasopharyngeal swabs' named entity 'risk factors' named entity 'coronavirus disease 2019' named entity 'dialysis' named entity 'hemodialysis' named entity 'Hemodialysis' named entity 'virus' named entity 'Hemodialysis' named entity 'contact tracing' named entity 'symptom' named entity 'infection control' named entity 'nasopharyngeal' named entity 'Toronto' named entity 'intensive care unit' named entity 'infection' named entity 'IPAC' named entity 'dialysis' named entity 'American Society of Nephrology' named entity 'hemodialysis' named entity 'hemodialysis' named entity 'Hemodialysis' named entity 'hemodialysis' named entity 'Retrospective cohort study' named entity 'Hemodialysis' named entity 'Toronto' named entity 'hemodialysis' named entity 'hemodialysis' named entity 'personal protective equipment' named entity 'dialyzed' named entity 'SARS-CoV-2' named entity 'IPAC' named entity 'dialysis' named entity 'SARS-CoV-2' named entity 'symptom' named entity 'COVID' named entity 'IPAC' named entity 'hemodialysis' named entity 'SARS-CoV-2' named entity 'kidney failure' named entity 'hemodialysis' named entity 'COVID-19' named entity 'SARS-CoV-2' named entity 'asymptomatic' named entity 'infection' named entity 'face shield' named entity 'dialysis' named entity 'SARS-CoV-2' named entity 'symptom' named entity 'St. Michael's Hospital' named entity 'polymerase chain reaction' named entity 'dialysis' named entity 'nasopharyngeal swabs'

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