About: Anti-foot-and-mouth disease virus effects of Chinese herbal kombucha in vivo

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About: Anti-foot-and-mouth disease virus effects of Chinese herbal kombucha in vivo Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Anti-foot-and-mouth disease virus effects of Chinese herbal kombucha in vivo
Creator	Fu, Naifang He, Jijun Jiang, Shengjun Lv, Lv Wu, Juncai
Source	PMC
abstract	The foot and mouth disease virus (FMDV) is sensitive to acids and can be inactivated by exposure to low pH conditions. Spraying animals at risk of infection with suspensions of acid-forming microorganisms has been identified as a potential strategy for preventing FMD. Kombucha is one of the most strongly acid-forming symbiotic probiotics and could thus be an effective agent with which to implement this strategy. Moreover, certain Chinese herbal extracts are known to have broad-spectrum antiviral effects. Chinese herbal kombucha can be prepared by fermenting Chinese herbal extracts with a kombucha culture. Previous studies demonstrated that Chinese herbal kombucha prepared in this way efficiently inhibits FMDV replication in vitro. To assess the inhibitory effects of Chinese herbal kombucha against FMDV in vitro, swine challenged by intramuscular injection with 1000 SID(50) of swine FMDV serotype O strain O/China/99 after treatment with Chinese herbal kombucha were partially protected against infection, as demonstrated by a lack of clinical symptoms and qRT-PCR analysis. In a large scale field trial, spraying cattle in an FMD outbreak zone with kombucha protected against infection. Chinese herbal kombucha may be a useful probiotic agent for managing FMD outbreaks.
has issue date	2015-12-01(xsd:dateTime)
bibo:doi	10.1590/s1517-838246420140701
bibo:pmid	26691487
has license	cc-by-nc
sha1sum (hex)	4564dfbcb341f91caefc5a880a127a629416c1c6
schema:url	https://doi.org/10.1590/s1517-838246420140701
resource representing a document's title	Anti-foot-and-mouth disease virus effects of Chinese herbal kombucha in vivo
has PubMed Central identifier	PMC4704643
has PubMed identifier	26691487
schema:publication	Braz J Microbiol
resource representing a document's body	covid:4564dfbcb341f91caefc5a880a127a629416c1c6#body_text
is schema:about of	named entity 'ANTIVIRAL' named entity 'LARGE SCALE' named entity 'KNOWN' named entity '1000' named entity 'POTENTIAL' named entity 'AT RISK OF INFECTION' named entity 'INFECTION' named entity 'THE FOOT' named entity 'PROBIOTIC' named entity 'ACIDS' named entity 'PARTIALLY' named entity 'AFTER TREATMENT' named entity 'REPLICATION' named entity 'INTRAMUSCULAR INJECTION' named entity 'PREVENTING' named entity 'ACID' named entity 'EXTRACTS' named entity 'SPECTRUM' named entity 'LOW PH' named entity 'FMD' named entity 'STUDIES' named entity 'HERBAL' named entity 'SEROTYPE' named entity 'IN VITRO' named entity 'SENSITIVE TO' named entity 'WAY' named entity 'CLINICAL SYMPTOMS' named entity 'STRAIN' named entity 'MAY BE A' named entity 'effective' named entity 'animals' named entity 'extracts' named entity 'QRT-PCR' named entity 'KOMBUCHA' covid:arg/4564dfbcb341f91caefc5a880a127a629416c1c6 named entity 'PREPARED' named entity 'HAVE' named entity 'OUTBREAK' named entity 'CULTURE' named entity 'BROAD' named entity 'STRATEGY' named entity 'MANAGING' named entity 'ANIMALS' named entity 'EFFECTS' named entity 'KOMBUCHA' named entity 'FOOT-AND-MOUTH DISEASE VIRUS' named entity 'IN VIVO' named entity 'INACTIVATED' named entity 'AGENT' named entity 'INHIBITORY' named entity 'CHINESE' named entity 'ZONE' named entity 'SWINE' named entity 'PCR ANALYSIS' named entity 'SYMBIOTIC' named entity 'SPRAYING' named entity 'CHINESE' named entity 'FMDV' named entity 'PROBIOTICS' named entity 'SID' named entity 'CONDITIONS' named entity 'FORMING' named entity 'CATTLE' named entity 'MICROORGANISMS' named entity 'EFFECTIVE' named entity 'EXPOSURE TO' named entity 'TRIAL' named entity 'HERBAL' named entity 'SUSPENSIONS' named entity 'LACK' named entity 'FIELD' named entity 'FOOT AND MOUTH DISEASE VIRUS' named entity 'EFFECTS' named entity 'IDENTIFIED' named entity 'CERTAIN' named entity 'ASSESS' named entity 'PREVIOUS'

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