About: Epidemiological and initial clinical characteristics of patients with family aggregation of COVID-19

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Epidemiological and initial clinical characteristics of patients with family aggregation of COVID-19 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Epidemiological and initial clinical characteristics of patients with family aggregation of COVID-19
Creator	Wu, Jing Jia, Bei Huang, Wen-Xiang Liu, He-Lei Xia, Hong Xia, Xiao-Ying
Source	Elsevier; Medline; PMC
abstract	Abstract Background Since December 2019, a new outbreak of the coronavirus disease 2019 (COVID-19) in Wuhan (Hubei, China) and rapidly spread throughout China, however, confirmed cases are still increasing worldwide. Objectives To investigate the epidemiological history and initial clinical characteristics of 10 patients with family aggregation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in Western Chongqing, China. Study design Ten patients positive for SARS-CoV-2 nucleic acid detection by real time Reverse Transcription-Polymerase Chain Reaction (RT-PCR), were collected from The People's Hospital of Dazu District, Chongqing. Epidemiological data and laboratory and imaging results were collected on the first day of admission, and analyzed based on the Diagnosis and Treatment Guideline for COVID-19 (5th edition, China). Results Of the 10 cases, case A had a history of a temporary stay in Wuhan and transmitted the virus to the others through family gathering, living together, and sharing vehicles. The average age was 56.5 years (± 11.16), six patients were males, and the incubation period was 2–14 days. Dry cough was the main symptom, followed by fever and fatigue. Most patients were clinically classified as ordinary-type, with three cases being severe-type. Chest computed tomography results were nonspecific, mainly with ground-glass attenuation and/or shadow images. Extensive lesion distribution was seen in severe cases. CD4+ lymphocyte counts were 61, 180, and 348 cells/uL in severe-type patients, respectively. Notably, viral nucleic acid values in nasopharyngeal swabs were lower (19, 25, and 26) than those of ordinary-type patients, suggesting a higher viral load. Neutrophil-lymphocyte ratio (NLR) was also higher in severe-type patients Conclusions Initial examination results of lower CD4+ lymphocyte counts and RT-PCR-CT values coupled with higher NLR may indicate the severity of COVID-19 infection for these family clusters.
has issue date	2020-06-30(xsd:dateTime)
bibo:doi	10.1016/j.jcv.2020.104360
bibo:pmid	32305025
has license	els-covid
sha1sum (hex)	43e94b156dd3088b39c967b0cfee10632fb69fcf
schema:url	https://doi.org/10.1016/j.jcv.2020.104360
resource representing a document's title	Epidemiological and initial clinical characteristics of patients with family aggregation of COVID-19
has PubMed Central identifier	PMC7151291
has PubMed identifier	32305025
schema:publication	Journal of Clinical Virology
resource representing a document's body	covid:43e94b156dd3088b39c967b0cfee10632fb69fcf#body_text
is schema:about of	named entity 'values' named entity 'collected' named entity 'transmitted' named entity 'CD4+' named entity 'patients' named entity 'viral' named entity 'worldwide' named entity 'aggregation' named entity 'SARS-CoV-2' named entity 'Chest' named entity 'clusters' named entity 'Dry cough' named entity 'patients' named entity 'higher' named entity 'cells' named entity 'symptom' named entity 'cases' named entity 'The' named entity 'cases' named entity 'patients' named entity 'acid' named entity 'detection' named entity 'Results' named entity 'virus' named entity 'COVID-19' named entity 'lymphocyte' named entity 'lesion' named entity 'viral load' named entity 'Chongqing' named entity 'China' named entity 'clinical characteristics' named entity 'RT-PCR' named entity 'epidemiological' named entity 'CD4+ lymphocyte' named entity 'Dazu District' named entity 'clinical characteristics' named entity 'bacteremia' named entity 'nursing records' named entity 'Guangzhou' named entity 'virus' named entity 'cellular immunity' named entity 'Wuhan' named entity 'China' named entity 'platelet count' named entity 'inflammatory response' named entity 'fatigue' named entity 'nucleic acids' named entity 'fatigue' named entity 'cough' named entity 'COVID-19' named entity 'lymphocyte' named entity 'protein' named entity 'respiratory symptom' named entity 'symptom' named entity 'chest CT' named entity 'immune function' named entity 'gene' named entity 'CD4' named entity 'Prevention and Control' named entity 'Chongqing' named entity 'Foshan' named entity 'antigen' named entity 'lymphocytes' named entity 'incubation period' named entity 'coronavirus' named entity 'doi' named entity 'acute pyelonephritis' named entity 'virus' named entity 'partial pressure' named entity 'CRP' named entity 'informed consent' named entity 'clinical characteristics' named entity 'shortness of breath' named entity 'liver cirrhosis' named entity 'cellular immunity' named entity 'renal function'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software