About: A Compact Immunoassay Platform Based on a Multicapillary Glass Plate

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A Compact Immunoassay Platform Based on a Multicapillary Glass Plate
Creator	Nakajima, Hizuru Uchiyama, Katsumi Xue, Shuhua Yang, Jianmin Zeng, Hulie
Source	Medline; PMC
abstract	A highly sensitive, rapid immunoassay performed in the multi-channels of a micro-well array consisting of a multicapillary glass plate (MCP) and a polydimethylsiloxane (PDMS) slide is described. The micro-dimensions and large surface area of the MCP permitted the diffusion distance to be decreased and the reaction efficiency to be increased. To confirm the concept of the method, human immunoglobulin A (h-IgA) was measured using both the proposed immunoassay system and the traditional 96-well plate method. The proposed method resulted in a 1/5-fold decrease of immunoassay time, and a 1/56-fold cut in reagent consumption with a 0.05 ng/mL of limit of detection (LOD) for IgA. The method was also applied to saliva samples obtained from healthy volunteers. The results correlated well to those obtained by the 96-well plate method. The method has the potential for use in disease diagnostic or on-site immunoassays.
has issue date	2014-05-23(xsd:dateTime)
bibo:doi	10.3390/s140509132
bibo:pmid	24859022
has license	cc-by
sha1sum (hex)	4055104522be7b53cb86035004c9406b118199f7
schema:url	https://doi.org/10.3390/s140509132
resource representing a document's title	A Compact Immunoassay Platform Based on a Multicapillary Glass Plate
has PubMed Central identifier	PMC4063063
has PubMed identifier	24859022
schema:publication	Sensors (Basel)
resource representing a document's body	covid:4055104522be7b53cb86035004c9406b118199f7#body_text
is schema:about of	named entity 'IMMUNOASSAY' named entity 'proposed' named entity 'array' named entity 'immunoassay' named entity 'slide' named entity 'samples' named entity 'PLATE' named entity 'GLASS' named entity 'DECREASED' named entity 'INCREASED' named entity 'POTENTIAL' named entity 'CONSUMPTION' named entity 'HUMAN IMMUNOGLOBULIN A' named entity 'IMMUNOASSAY' named entity 'MICRO-' named entity 'ARRAY' named entity 'LIMIT OF DETECTION' named entity 'IGA' named entity 'SITE' named entity '0.05' named entity 'PERMITTED' named entity 'IMMUNOASSAYS' named entity 'POLYDIMETHYLSILOXANE' named entity 'RESULTS' named entity 'PLATE' named entity 'USE' named entity 'APPLIED' named entity 'DISEASE DIAGNOSTIC' named entity 'PROPOSED' named entity '28H' named entity 'SLIDE' named entity 'USING' named entity 'MCP' named entity 'DIFFUSION' named entity 'REACTION' named entity 'RAPID IMMUNOASSAY' named entity 'DIMENSIONS' named entity 'SYSTEM' named entity 'PLATFORM' named entity 'COMPACT' named entity 'BASED' named entity 'SAMPLES' named entity 'SALIVA' named entity 'CONCEPT' named entity 'OBTAINED BY' named entity 'HEALTHY VOLUNTEERS' named entity 'DISTANCE' named entity 'FOLD DECREASE' named entity 'EFFICIENCY' named entity 'CORRELATED' named entity 'HIGHLY SENSITIVE' named entity 'PERFORMED' named entity 'OBTAINED' named entity 'FOLD' named entity 'CUT' named entity 'CONFIRM' named entity 'MEASURED' named entity 'MULTI' named entity 'METHOD' named entity 'TRADITIONAL' named entity 'CHANNELS' named entity 'DESCRIBED' named entity 'LARGE' named entity 'GLASS' named entity 'SURFACE AREA' named entity 'TIME' named entity 'REAGENT' covid:arg/4055104522be7b53cb86035004c9406b118199f7 named entity 'plate' named entity 'reagent' named entity 'concept' named entity 'glass plate' named entity 'MCP' named entity 'highly' named entity 'performed' named entity 'immunoassay' named entity 'IgA'

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