About: Preoperative miRNA-208a as a Predictor of Postoperative Complications in Children with Congenital Heart Disease Undergoing Heart Surgery

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Preoperative miRNA-208a as a Predictor of Postoperative Complications in Children with Congenital Heart Disease Undergoing Heart Surgery Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Preoperative miRNA-208a as a Predictor of Postoperative Complications in Children with Congenital Heart Disease Undergoing Heart Surgery
Creator	Bar-Yosef, Omer Bolkier, Yoav Mishali, David Nevo-Caspi, Yael Paret, Gidi Tirosh-Wagner, Tal Vardi, Amir Zloto, Keren
Source	PMC
abstract	Major perioperative cardiovascular events are important causes of morbidity in pediatric patients with congenital heart disease who undergo reparative surgery. Current preoperative clinical risk assessment strategies have poor accuracy for identifying patients who will sustain adverse events following heart surgery. There is an ongoing need to integrate clinical variables with novel technology and biomarkers to accurately predict outcome following pediatric heart surgery. We tested whether preoperative levels of miRNAs-208a can serve as such a biomarker. Serum samples were obtained from pediatric patients immediately before heart surgery. MiRNA-208a was quantified by RQ-PCR. Correlations between the patient’s clinical variables and miRNA levels were tested. Lower levels of preoperative miRNA-208a correlated with and could predict the appearance of postoperative cardiac and inflammatory complications. MiRNA-208a may serve as a biomarker for the prediction of patients who are at risk to develop complications following surgery for the repair of congenital heart defects.
has issue date	2019-11-15(xsd:dateTime)
bibo:doi	10.1007/s12265-019-09921-1
bibo:pmid	31732917
has license	no-cc
sha1sum (hex)	3f3d6a0fef87fda683afc00da38028fbe57fa5b2
schema:url	https://doi.org/10.1007/s12265-019-09921-1
resource representing a document's title	Preoperative miRNA-208a as a Predictor of Postoperative Complications in Children with Congenital Heart Disease Undergoing Heart Surgery
has PubMed Central identifier	PMC7224117
has PubMed identifier	31732917
schema:publication	J Cardiovasc Transl Res
resource representing a document's body	covid:3f3d6a0fef87fda683afc00da38028fbe57fa5b2#body_text
is schema:about of	named entity 'SAMPLES' named entity 'BIOMARKER' named entity 'CONGENITAL HEART DISEASE' named entity 'MAJOR' named entity 'Centrifugation' named entity 'miRNA' named entity 'serum' named entity 'miRNAs' named entity 'pediatric' named entity 'QPCR' named entity 'lactate' named entity 'nucleotides' named entity 'reperfusion' named entity 'Spearman correlation' named entity 'exact mechanism' named entity 'life-threatening' named entity 'oxygen saturation' named entity '0.01' named entity 'miRNA' named entity 'ROC' named entity 'non-normally distributed' named entity 'ECMO' named entity 'cDNA' named entity 'informed consent' named entity 'ectopic' named entity 'normoxic' named entity 'Aristotle' named entity 'cell death' named entity 'arrhythmia' named entity 'extracellular' named entity 'miRNA' named entity 'Helsinki declaration' named entity 'cyanotic' named entity 'Expression levels' named entity 'miRNA' named entity 'oxygen saturation' named entity '0.01' named entity 'congenital anomalies' named entity 'oxygen saturations' named entity 'confidence intervals' named entity 'miRNA' named entity 'miRNA' named entity 'CHD' named entity 'ACC' named entity '95% CI' named entity 'QPCR' named entity 'lactate' named entity '0.01' named entity 'miRNA' named entity 'creatinine levels' named entity 'Taqman' named entity 'ventilator support' named entity 'oxygen saturation' named entity 'miRNA' named entity 'miRNA' named entity 'Odds ratios' named entity 'normal distribution' named entity '1.14' named entity 'lactate' named entity 'expression levels' named entity 'biomarker' named entity 'miRNAs' named entity '99-1' named entity 'perioperative' named entity 'ROC' named entity 'Informed consent' named entity 'cardiac surgery' named entity 'extracellular RNA' named entity 'LOHs' named entity 'miRNA' named entity 'Logistic regression' named entity 'ROC' named entity 'open heart surgery' named entity 'cyanotic'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software