About: Non-neoformans Cryptococcal Infections: a Systematic Review

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Non-neoformans Cryptococcal Infections: a Systematic Review
Creator	Apisarnthanarak, A Mundy, L Khawcharoenporn, T
source	PMC
abstract	Non-neoformans cryptococci have been generally regarded as saprophytes and rarely reported as human pathogens. However, the incidence of infection due to these organisms has increased over the past 40 years, with Cryptococcus laurentii and Cryptococcus albidus, together, responsible for 80% of reported cases. Conditions associated with impaired cell-mediated immunity are important risks for non-neoformans cryptococcal infections and prior azole prophylaxis has been associated with antifungal resistance. The presence of invasive devices was a significant risk factor for Cryptococcus laurentii infection (adjusted OR = 8.7; 95% CI = 1.48–82.9; p = 0.003), while predictors for mortality included age ≥45 years (aOR = 8.4; 95% CI = 1.18–78.82; p = 0.004) and meningeal presentation (aOR = 7.0; 95% CI = 1.85–60.5; p= 0.04). Because clinical manifestations of non-neoformans cryptococcal infections are most often indistinguishable from Cryptococcus neoformans, a high index of suspicion remains important to facilitate early diagnosis and prompt treatment for such infections.
has issue date	2007-01-01(xsd:dateTime)
bibo:doi	10.1007/s15010-007-6142-8
bibo:pmid	17401707
has license	no-cc
sha1sum (hex)	36cdc7abbd11ee6db477e0b6fcdbc7eac4e1fb18
schema:url	https://doi.org/10.1007/s15010-007-6142-8
resource representing a document's title	Non-neoformans Cryptococcal Infections: a Systematic Review
has PubMed Central identifier	PMC7101977
has PubMed identifier	17401707
schema:publication	Infection
resource representing a document's body	covid:36cdc7abbd11ee6db477e0b6fcdbc7eac4e1fb18#body_text
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