About: Molecular Transducers of Physical Activity Consortium (MoTrPAC): Mapping the Dynamic Responses to Exercise

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Molecular Transducers of Physical Activity Consortium (MoTrPAC): Mapping the Dynamic Responses to Exercise
Creator	Snyder, Michael Walsh, Martin Cortese, Mirko Boulant, Steeve Adkins, Joshua Stanifer, Megan Walsh, S Alexandrov, Theodore Kee, Kraeusslich, Hans-Georg Mukenhirn, Markus Tracy, Russell Amar, David Amar, J Bartenschlager, Dasari, Surendra Drugan, Jonelle Fernández, Facundo Fernández, J Lindholm, C Lindholm, Malene Nogiec, Christopher Radom-Aizik, Shlomit Sanford, James Schenk, S Schenk, Simon Snyder, S Tracy, M Trappe, P Trappe, Scott Triana, Vanderboom, Patrick Vanderboom, R Zumaran, Camila
Source	Elsevier; Medline; PMC
abstract	Abstract Exercise provides a robust physiological stimulus that evokes cross-talk among multiple tissues that when repeated regularly (i.e., training) improves physiological capacity, benefits numerous organ systems and decreases the risk for premature mortality. However, a gap remains in identifying the detailed molecular signals induced by exercise that benefit health and prevent disease. The Molecular Transducers of Physical Activity Consortium (MoTrPAC) was established to address this gap and generate a molecular map of exercise. Preclinical and clinical studies will examine the systemic effects of endurance and resistance exercise across a range of ages and fitness levels by molecular probing of multiple tissues before and after acute and chronic exercise. From this multi-omic and bioinformatic analysis, a molecular map of exercise will be established. Altogether, MoTrPAC will provide a public database that is expected to enhance our understanding of the health benefits of exercise and to provide insight into how activity mitigates disease.
has issue date	2020-06-19(xsd:dateTime)
bibo:doi	10.1016/j.celrep.2020.107863
bibo:pmid	32610043
has license	els-covid
sha1sum (hex)	2e4c865ce5f063c3d04f3f05475274317b7242f7
schema:url	https://doi.org/10.1016/j.celrep.2020.107863
resource representing a document's title	Molecular Transducers of Physical Activity Consortium (MoTrPAC): Mapping the Dynamic Responses to Exercise
has PubMed Central identifier	PMC7303637
has PubMed identifier	32610043
schema:publication	Cell Rep
resource representing a document's body	covid:2e4c865ce5f063c3d04f3f05475274317b7242f7#body_text
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