About: The clinical data from 19 critically ill patients with coronavirus disease 2019: a single-centered, retrospective, observational study

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About: The clinical data from 19 critically ill patients with coronavirus disease 2019: a single-centered, retrospective, observational study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The clinical data from 19 critically ill patients with coronavirus disease 2019: a single-centered, retrospective, observational study
Creator	Zhao, Yan Ma, Jing Zhang, Hui Wang, Lu Liu, Peng Wang, Jie Chen, Jie Zhang, Jinping Li, Mei Chu, Tian Dong, Wangping Li, Hongye Tao, Ting Wan, Lun Wang, Morong Xie, Zhijuan Yuan, Wenling
Source	Medline; PMC
abstract	BACKGROUND: The objectives of this study were to analyze the clinical features of coronavirus disease 2019 (COVID-19) and evaluate the diagnosis and treatment. METHODS: A retrospective analysis of the clinical manifestation and auxiliary examination of 19 patients with COVID-19 from the Liyuan Hospital intensive care unit (ICU) between January 16, 2020 and February 20, 2020 was undertaken. RESULTS: There were 11 male and 8 female cases among the patients. The median (range) age was 73 (38–91) years. Of these patients, 8 (42.1%) had died and the median duration from ICU admission to death was 2 (interquartile range (IQR): 1–10.75) days. Seven of these 8 patients had underlying diseases. The auxiliary examination showed fever (68.4%), dry cough (15.8%), dyspnea (10.5%), and diarrhea (5.3%). All 19 cases showed ground-glass changes on chest computed tomography. Serum hypersensitive C-reactive protein (hs-CRP) and serum amylase A (SAA) were clearly increased in all of the cases. Among the 19 cases, there were 16 (84.2%) cases in which the total number of lymphocytes decreased, 12 cases (63%) had reduced liver function, and 11 cases (58%) had deviant results for fibrinogen (FIB) and D-dimer, in particular, the D-dimer level was significantly higher in the non-survivors compared with the survivors. CONCLUSION: There were more men than women among critically ill patients. All of the cases showed ground-glass changes on chest computed tomography and the vast majority of patients displayed fever and dry cough. The clinical laboratory indices change significantly, especially the D-dimer level among non-survivors.
has issue date	2020-04-21(xsd:dateTime)
bibo:doi	10.1007/s10389-020-01291-2
bibo:pmid	32318325
has license	no-cc
sha1sum (hex)	2dfa1f27d87881bc93d1521011a48c234f500113
schema:url	https://doi.org/10.1007/s10389-020-01291-2
resource representing a document's title	The clinical data from 19 critically ill patients with coronavirus disease 2019: a single-centered, retrospective, observational study
has PubMed Central identifier	PMC7171052
has PubMed identifier	32318325
schema:publication	Z Gesundh Wiss
resource representing a document's body	covid:2dfa1f27d87881bc93d1521011a48c234f500113#body_text
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