About: Viral aetiology influenza like illnesses in Santa Cruz, Bolivia (2010

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About: Viral aetiology influenza like illnesses in Santa Cruz, Bolivia (2010–2012) Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Viral aetiology influenza like illnesses in Santa Cruz, Bolivia (2010–2012)
Creator	Baronti, Cécile Bessaud, Maël Delangue, Julie Piorkowski, Géraldine Roca Sanchez, Yelin Thirion-Perrier, Laurence De Lamballerie, Xavier Aguilera, Gabriela Avila Ardaya, Cinthia Cruz, Guzman, Jimmy Loayza Mafayle, Roxana Riera, Javier
Source	Medline; PMC
abstract	BACKGROUND: Acute respiratory infections represent a serious public health issue worldwide but virological aetiologies of Influenza Like Illnesses (ILIs) remain largely unknown in developing countries. This study represents the first attempt to characterise viral aetiologies of ILIs in Bolivia. METHODS: It was performed in Santa Cruz city from January 2010 to September 2012, based on 564 naso-pharyngeal swabs collected in a National Reference Laboratory and real-time PCR techniques, viral cultures and phylogenetic analyses. RESULTS: 50.2% of samples were positive for at least one virus with influenza viruses (Flu A: ~15%; Flu B: ~9%), rhinoviruses (~8%), coronaviruses (~5%) and hRSV (~4%) being the most frequently identified. The pattern of viral infections varied according to age groups. The elucidation rate was the highest (>60%) amongst patients under 10 yo and the lowest (<40%) amongst patients ≥60 yo. Nearly 3% of samples showed dual viral infections. Epidemiological peaks were associated with a predominant virus but generally included 30-50% of infections by different viruses. Unexpectedly, the frequency of influenza in the 0–4 yo population was very low and a complete hRSV eclipse occurred in 2011. Genetic analyses indicated that distinct evolutionary lineages of Flu A(H1N1)pdm2009, Flu A/H3N2 and Flu B have co-circulated in Bolivia in the study period, originating from Central and North America, Europe, Asia and Australia. CONCLUSION: Our results emphasise the requirement for a reinforced epidemiological and genetic follow-up of influenza and other ILIs in Bolivia to further inform the preparation of vaccines used in the region, guide vaccination campaigns and improve the medical management of patients.
has issue date	2014-02-24(xsd:dateTime)
bibo:doi	10.1186/1743-422x-11-35
bibo:pmid	24564892
has license	cc-by
sha1sum (hex)	2a7fdc03389aef740cb9d6de762e96e52473b236
schema:url	https://doi.org/10.1186/1743-422x-11-35
resource representing a document's title	Viral aetiology influenza like illnesses in Santa Cruz, Bolivia (2010–2012)
has PubMed Central identifier	PMC4015617
has PubMed identifier	24564892
schema:publication	Virol J
resource representing a document's body	covid:2a7fdc03389aef740cb9d6de762e96e52473b236#body_text
is schema:about of	named entity 'INFLUENZA' named entity 'viral infections' named entity 'virus' named entity 'Acute' named entity 'ILIs' named entity 'study' named entity 'Reference' named entity 'cultures' named entity 'swabs' named entity 'UNDER 10' covid:arg/2a7fdc03389aef740cb9d6de762e96e52473b236 named entity 'POPULATION' named entity 'LOWEST' named entity 'ECLIPSE' named entity 'PREPARATION' named entity 'EPIDEMIOLOGICAL' named entity 'TECHNIQUES' named entity 'PERIOD' named entity 'ASSOCIATED WITH' named entity 'INFORM' named entity 'ACUTE RESPIRATORY INFECTIONS' named entity 'SAMPLES' named entity 'DEVELOPING COUNTRIES' named entity 'VIRUS' named entity 'PUBLIC HEALTH' named entity '50%' named entity 'BACKGROUND' named entity 'REFERENCE LABORATORY' named entity 'VIRUSES' named entity 'FOLLOW-UP' named entity 'INDICATED' named entity 'MEDICAL MANAGEMENT' named entity 'ILLNESSES' named entity 'CONCLUSION' named entity 'INCLUDED' named entity 'FREQUENTLY' named entity 'HIGHEST' named entity 'PEAKS' named entity 'INFECTIONS' named entity 'POSITIVE FOR' named entity 'NATIONAL' named entity 'BASED' named entity 'PATIENTS' named entity 'REGION' named entity 'ACCORDING' named entity 'NASO' named entity 'BOLIVIA' named entity 'WORLDWIDE' named entity 'NORTH AMERICA' named entity 'BEING' named entity 'RATE' named entity 'COMPLETE' named entity 'VIRAL INFECTIONS' named entity 'PATTERN' named entity 'HRSV' named entity 'VIRAL' named entity 'GENETIC' named entity 'OCCURRED' named entity 'INFLUENZA' named entity 'CULTURES' named entity 'PHARYNGEAL' named entity 'AUSTRALIA' named entity 'REPRESENT' named entity 'SWABS' named entity 'JANUARY' named entity 'VIROLOGICAL' named entity 'STUDY' named entity 'SANTA CRUZ' named entity 'REQUIREMENT'

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