About: The First Identification and Retrospective Study of Severe Fever With Thrombocytopenia Syndrome in Japan

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About: The First Identification and Retrospective Study of Severe Fever With Thrombocytopenia Syndrome in Japan Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The First Identification and Retrospective Study of Severe Fever With Thrombocytopenia Syndrome in Japan
Creator	Maeda, Ken Katano, Harutaka Fukushi, Shuetsu Morikawa, Shigeru Nagata, Noriyo Saijo, Masayuki Fukuma, Aiko Shimojima, Masayuki Tani, Hideki Yoshikawa, Tomoki Kurane, Ichiro Hasegawa, Hideki Sato, Yuko Suzuki, Tadaki Fukumoto, Hitomi Nakajima, Noriko Oishi, Kazunori Yamagishi, Takuya Doi, Kazuko Fukushima, Kazuko Honda, Masahiro Ishido, Aki Kamei, Toshiaki Kaneyuki, Shozo Nakajima, Kensuke Ninomiya, Daisuke Ogata, Momoko Okuda, Masaru Saito, Tomoya Sakaguchi, Shota Sakai, Takenori Senba, Takanori Shigeoka, Toru Takahashi, Toru Tominaga, Takayuki Umeki, Kazunori
Source	PMC
abstract	Background. Severe fever with thrombocytopenia syndrome (SFTS) is caused by SFTS virus (SFTSV), a novel bunyavirus reported to be endemic in central and northeastern China. This article describes the first identified patient with SFTS and a retrospective study on SFTS in Japan. Methods. Virologic and pathologic examinations were performed on the patient's samples. Laboratory diagnosis of SFTS was made by isolation/genome amplification and/or the detection of anti-SFTSV immunoglobulin G antibody in sera. Physicians were alerted to the initial diagnosis and asked whether they had previously treated patients with symptoms similar to those of SFTS. Results. A female patient who died in 2012 received a diagnosis of SFTS. Ten additional patients with SFTS were then retrospectively identified. All patients were aged ≥50 years and lived in western Japan. Six cases were fatal. The ratio of males to females was 8:3. SFTSV was isolated from 8 patients. Phylogenetic analyses indicated that all of the Japanese SFTSV isolates formed a genotype independent to those from China. Most patients showed symptoms due to hemorrhage, possibly because of disseminated intravascular coagulation and/or hemophagocytosis. Conclusions. SFTS has been endemic to Japan, and SFTSV has been circulating naturally within the country.
has issue date	2014-03-15(xsd:dateTime)
bibo:doi	10.1093/infdis/jit603
bibo:pmid	24231186
has license	no-cc
sha1sum (hex)	25b922ea09b0f4df47641787e559e3f5a07dc13b
schema:url	https://doi.org/10.1093/infdis/jit603
resource representing a document's title	The First Identification and Retrospective Study of Severe Fever With Thrombocytopenia Syndrome in Japan
has PubMed Central identifier	PMC7107388
has PubMed identifier	24231186
schema:publication	J Infect Dis
resource representing a document's body	covid:25b922ea09b0f4df47641787e559e3f5a07dc13b#body_text
is schema:about of	named entity 'RETROSPECTIVE STUDY' named entity 'This' named entity 'With' named entity 'Thrombocytopenia' named entity 'NOVEL' named entity 'REPORTED' named entity 'JAPAN' named entity 'SEVERE FEVER WITH THROMBOCYTOPENIA SYNDROME' named entity 'CHINA' named entity 'SEVERE FEVER WITH THROMBOCYTOPENIA SYNDROME' named entity 'IDENTIFICATION' named entity 'JAPAN' named entity 'IDENTIFIED' named entity 'CAUSED BY' named entity 'ARTICLE' named entity 'PATIENT' named entity 'BUNYAVIRUS' named entity 'CENTRAL' named entity 'SFTS VIRUS' named entity 'BACKGROUND' named entity 'RETROSPECTIVE STUDY' named entity 'ENDEMIC' named entity 'NORTHEASTERN' named entity 'fever' named entity 'Fever' named entity 'Retrospective' named entity 'retrospective study' named entity 'bunyavirus' named entity 'SFTS' named entity 'Japan' named entity 'SFTS' named entity 'endemic' named entity 'Japan' named entity 'RNA' named entity 'RNA' named entity 'SFTS virus' named entity 'immunoglobulin' named entity 'gastrointestinal tract' named entity 'Viral' named entity 'RNA' named entity 'blood culture' named entity 'Japan' named entity '1, 2' named entity 'low platelet count' named entity 'Bone marrow aspiration' named entity 'SFTSV'

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