About: Diffuse alveolar hemorrhage in infants: Report of five cases

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Diffuse alveolar hemorrhage in infants: Report of five cases
Creator	Janssen, A Boboli, H Broux, I Gkogkou, E Kempeneers, C M-C, Seghaye Mastouri, M Seghaye, M.-C Viellevoye, R
Source	Elsevier; Medline; PMC
abstract	Diffuse alveolar hemorrhage (DAH) is a rare life-threatening condition in children. In this entity, the bleeding originates from the pulmonary microvasculature as a result of microvascular damage leading to blood leakage into the alveolar spaces. DAH can occur as an isolated medical entity or may be associated with other organ system injury or dysfunction. The classic triad of symptoms includes hemoptysis, anemia and diffuse pulmonary infiltrates. Hemoptysis is the usual presenting symptom but is not constant. A variety of diseases is associated with the development of DAH. Current classification organize the etiologies of diffuse alveolar hemorrhage based on the presence of severe immune disorders (such as systemic vasculitis and collagenosis) or non-immunodeficiency disorders (with an identified cardiac or non-cardiac origin, or idiopathic). The five cases of DAH presented in this study were all diagnosed in full-term infants, four males and one female, with normal neonatal adaptation and without family history of notable diseases. In all cases the diagnosis was made between the age of three and eighteen weeks-old. Moreover, all five patients, at the time of diagnosis, presented with hemoptysis, mild or severe dyspnea, anemia and abnormal chest X-rays. Consequently, the diagnosis of DAH was strongly suspected and, eventually, confirmed by bronchoscopy. Additional laboratory tests, as well as selected serologic and radiographic studies were performed in order to identify a specific etiology. The final diagnoses reflect a variety of causes: infections, idiopathic pulmonary hemosiderosis, accidental suffocation and Heiner syndrome. Treatment included oral corticosteroids except from one patient that received antimicrobial therapy.
has issue date	2020-06-11(xsd:dateTime)
bibo:doi	10.1016/j.rmcr.2020.101121
bibo:pmid	32802736
has license	no-cc
sha1sum (hex)	1c691168b0097773e142e388b6cec14b67dbff16
schema:url	https://doi.org/10.1016/j.rmcr.2020.101121
resource representing a document's title	Diffuse alveolar hemorrhage in infants: Report of five cases
has PubMed Central identifier	PMC7289102
has PubMed identifier	32802736
schema:publication	Respir Med Case Rep
resource representing a document's body	covid:1c691168b0097773e142e388b6cec14b67dbff16#body_text
is schema:about of	named entity 'originates' named entity 'The classic' named entity 'injury' named entity 'anemia' named entity 'symptoms' named entity 'hemoptysis' named entity 'DAH' named entity 'alveolar spaces' named entity 'Blood culture' named entity 'reintubation' named entity 'anemia' named entity 'computed tomography' named entity 'Trachomatis' named entity 'serologic' named entity 'IgE' named entity 'macrophages' named entity 'etiology' named entity 'central cyanosis' named entity 'IgG' named entity 'IgA' named entity 'fever' named entity 'packed red blood cells' named entity 'Chest x-ray' named entity 'supportive therapy' named entity 'ventilatory support' named entity 'hypoxemia' named entity 'cow's milk' named entity 'precipitins' named entity 'pulmonary auscultation' named entity 'hemosiderosis' named entity 'cow's milk' named entity 'serum' named entity 'radiographic' named entity '21 days' named entity 'hypoallergenic' named entity 'fever' named entity 'ventilatory support' named entity 'bronchial' named entity 'echocardiography' named entity 'ground-glass opacities' named entity 'angiography' named entity 'pulmonary hemorrhage' named entity 'clarithromycin' named entity 'lung' named entity 'extubation' named entity 'hematocrit' named entity 'respiratory acidosis' named entity 'left lower lobe' named entity 'idiopathic' named entity 'SpO2' named entity 'anemia' named entity 'packed red blood cells' named entity 'differential diagnosis' named entity 'pathology' named entity 'IgM' named entity 'WBC' named entity 'lymphocytes' named entity 'prednisone' named entity 'lung' named entity 'milk' named entity 'amino acid' named entity 'prednisolone' named entity 'parenchymal' named entity 'alveolar' named entity 'vascular malformation' named entity 'intravenous antibiotics' named entity 'immunosuppressive therapy' named entity 'volume expansion' named entity 'Chest CT' named entity 'Thoracic' named entity 'IgE' named entity 'SpO2' named entity 'Physical examination'

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