About: Pathogenesis, imaging and clinical characteristics of CF and non-CF bronchiectasis

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Pathogenesis, imaging and clinical characteristics of CF and non-CF bronchiectasis
Creator	Chandrasekaran, Ravishankar Griese, Matthias Hartl, Dominik Schäfer, Jürgen Chotirmall, Sanjay
source	Medline; PMC
abstract	Bronchiectasis is a common feature of severe inherited and acquired pulmonary disease conditions. Among inherited diseases, cystic fibrosis (CF) is the major disorder associated with bronchiectasis, while acquired conditions frequently featuring bronchiectasis include post-infective bronchiectasis and chronic obstructive pulmonary disease (COPD). Mechanistically, bronchiectasis is driven by a complex interplay of inflammation and infection with neutrophilic inflammation playing a predominant role. The clinical characterization and management of bronchiectasis should involve a precise diagnostic workup, tailored therapeutic strategies and pulmonary imaging that has become an essential tool for the diagnosis and follow-up of bronchiectasis. Prospective future studies are required to optimize the diagnostic and therapeutic management of bronchiectasis, particularly in heterogeneous non-CF bronchiectasis populations.
has issue date	2018-05-22(xsd:dateTime)
bibo:doi	10.1186/s12890-018-0630-8
bibo:pmid	29788954
has license	cc-by
sha1sum (hex)	16844dca24405d3c94a4366cd94598a6a7357fc8
schema:url	https://doi.org/10.1186/s12890-018-0630-8
resource representing a document's title	Pathogenesis, imaging and clinical characteristics of CF and non-CF bronchiectasis
has PubMed Central identifier	PMC5964733
has PubMed identifier	29788954
schema:publication	BMC Pulm Med
resource representing a document's body	covid:16844dca24405d3c94a4366cd94598a6a7357fc8#body_text
is schema:about of	named entity 'bronchiectasis' named entity 'management' named entity 'tailored' named entity 'NON-' named entity 'STUDIES' named entity 'PREDOMINANT' named entity 'PLAYING' named entity 'FUTURE' named entity 'PULMONARY DISEASE' named entity 'IS A' named entity 'FEATURE' named entity 'INFLAMMATION' named entity 'MANAGEMENT' named entity 'DRIVEN' named entity 'CHARACTERIZATION' named entity 'FOLLOW-UP' named entity 'CLINICAL' named entity 'COMPLEX' named entity 'TAILORED' named entity 'ROLE' named entity 'CHRONIC OBSTRUCTIVE PULMONARY DISEASE' named entity 'INFECTION' named entity 'OPTIMIZE' named entity 'IMAGING' named entity 'PROSPECTIVE' named entity 'INHERITED' named entity 'DISORDER ASSOCIATED' named entity 'REQUIRED' named entity 'DIAGNOSTIC' named entity 'CONDITIONS' named entity 'TOOL' named entity 'THERAPEUTIC' named entity 'BRONCHIECTASIS' named entity 'BRONCHIECTASIS' named entity 'PATHOGENESIS' named entity 'CLINICAL CHARACTERISTICS' named entity 'ESSENTIAL' named entity 'INCLUDE' named entity 'DIAGNOSIS' named entity 'NON-' named entity 'CYSTIC FIBROSIS' named entity 'A COMMON' named entity 'PULMONARY IMAGING' named entity 'MAJOR' named entity 'FREQUENTLY' named entity 'ASSOCIATED WITH' named entity 'HETEROGENEOUS' named entity 'SEVERE' named entity 'STRATEGIES' named entity 'POST-INFECTIVE BRONCHIECTASIS' named entity 'DISEASES' named entity 'NEUTROPHILIC INFLAMMATION' named entity 'PRECISE' named entity 'POPULATIONS' named entity 'ACQUIRED' covid:arg/16844dca24405d3c94a4366cd94598a6a7357fc8 named entity 'management' named entity 'frequently' named entity 'infection' named entity 'bronchiectasis' named entity 'optimize' named entity 'conditions' named entity 'bronchiectasis' named entity 'severe' named entity 'common' named entity 'involve' named entity 'featuring' named entity 'Pathogenesis' named entity 'pulmonary disease' named entity 'inflammation' named entity 'neutrophilic' named entity 'follow-up' named entity 'future studies' named entity 'bronchiectasis' named entity 'bronchiectasis' named entity 'bronchiectasis' named entity 'chronic obstructive pulmonary disease'

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