About: Estimation of basic reproduction number of the Middle East respiratory syndrome coronavirus (MERS-CoV) during the outbreak in South Korea, 2015

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Estimation of basic reproduction number of the Middle East respiratory syndrome coronavirus (MERS-CoV) during the outbreak in South Korea, 2015 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Estimation of basic reproduction number of the Middle East respiratory syndrome coronavirus (MERS-CoV) during the outbreak in South Korea, 2015
Creator	Chang, Hyuk-Jun
Source	Medline; PMC
abstract	BACKGROUND: In South Korea, an outbreak of Middle East respiratory syndrome (MERS) occurred in 2015. It was the second largest MERS outbreak. As a result of the outbreak in South Korea, 186 infections were reported, and 36 patients died. At least 16,693 people were isolated with suspicious symptoms. This paper estimates the basic reproduction number of the MERS coronavirus (CoV), using data on the spread of MERS in South Korea. METHODS: The basic reproduction number of an epidemic is defined as the average number of secondary cases that an infected subject produces over its infectious period in a susceptible and uninfected population. To estimate the basic reproduction number of the MERS-CoV, we employ data from the 2015 South Korea MERS outbreak and the susceptible-infected-removed (SIR) model, a mathematical model that uses a set of ordinary differential equations (ODEs). RESULTS: We fit the model to the epidemic data of the South Korea outbreak minimizing the sum of the squared errors to identify model parameters. Also we derive the basic reproductive number as the terms of the parameters of the SIR model. Then we determine the basic reproduction number of the MERS-CoV in South Korea in 2015 as 8.0977. It is worth comparing with the basic reproductive number of the 2014 Ebola outbreak in West Africa including Guinea, Sierra Leone, and Liberia, which had values of 1.5–2.5. CONCLUSIONS: There was no intervention to control the infection in the early phase of the outbreak, thus the data used here provide the best conditions to evaluate the epidemic characteristics of MERS, such as the basic reproduction number. An evaluation of basic reproduction number using epidemic data could be problematic if there are stochastic fluctuations in the early phase of the outbreak, or if the report is not accurate and there is bias in the data. Such problems are not relevant to this study because the data used here were precisely reported and verified by Korea Hospital Association.
has issue date	2017-06-13(xsd:dateTime)
bibo:doi	10.1186/s12938-017-0370-7
bibo:pmid	28610609
has license	cc-by
sha1sum (hex)	07bf7b392feb438d436be66e2bdfe7513320231b
schema:url	https://doi.org/10.1186/s12938-017-0370-7
resource representing a document's title	Estimation of basic reproduction number of the Middle East respiratory syndrome coronavirus (MERS-CoV) during the outbreak in South Korea, 2015
has PubMed Central identifier	PMC5470331
has PubMed identifier	28610609
schema:publication	Biomed Eng Online
resource representing a document's body	covid:07bf7b392feb438d436be66e2bdfe7513320231b#body_text
is schema:about of	named entity 'BACKGROUND' named entity '2015' named entity 'MIDDLE EAST RESPIRATORY SYNDROME ' named entity 'INFECTIONS' named entity 'ESTIMATES' named entity 'SECOND' named entity 'MERS' named entity 'PAPER' named entity 'SYMPTOMS' named entity 'NUMBER OF' named entity 'SUSPICIOUS' named entity 'PATIENTS' named entity 'USING' named entity 'SOUTH KOREA' named entity 'ESTIMATION' named entity 'OCCURRED' named entity 'DATA' named entity 'BASIC REPRODUCTION NUMBER' named entity '2015' named entity 'NUMBER OF' named entity 'OUTBREAK' named entity 'AS A RESULT OF' named entity 'MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS' named entity 'SOUTH KOREA' named entity 'LARGEST' named entity 'ISOLATED' named entity 'OUTBREAK' named entity 'SPREAD' named entity 'BASIC REPRODUCTION NUMBER' named entity 'REPORTED' named entity 'DIED' named entity 'PEOPLE' named entity 'MERS outbreak' named entity 'South Korea' named entity 'Middle East respiratory syndrome coronavirus' named entity 'infectivity' named entity 'epidemic' named entity 'birth and death' named entity 'MERS' named entity 'basic reproduction number' named entity 'reproductive number' named entity 'epidemic curve' named entity 'basic reproduction number' named entity 'SIR model' named entity 'reproduction number' named entity 'reproduction number' named entity 'physical quantity' named entity 'SIR model' named entity 'sophisticated approach' named entity 'reproduction number' named entity 'basic reproduction number' named entity 'latent period' named entity 'South Korea' named entity 'MERS-CoV' named entity 'basic reproduction number' named entity 'Saudi Arabia' named entity 'SIR model' named entity 'epidemic' named entity 'epidemic' named entity 'epidemic' named entity 'mathematical model' named entity 'SARS' named entity 'SIR model' named entity 'MERS' named entity 'initial condition' named entity 'mathematical model' named entity 'epidemic' named entity 'South Korea in 2015' named entity 'epidemic' named entity 'birth and death' named entity 'mathematical model' named entity 'South Korea' named entity 'basic reproduction number' named entity 'sum of squared error' named entity 'MERS outbreak' named entity 'epidemic' named entity 'transmissibility' named entity 'South Korea' named entity 'CoV' named entity 'coronavirus' named entity 'MERS-CoV'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software