About: Identification of B‐cell epitopes on the betanodavirus capsid protein

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Identification of B‐cell epitopes on the betanodavirus capsid protein Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Identification of B‐cell epitopes on the betanodavirus capsid protein
Creator	Adams, A Costa, J Thompson, K Bron, J Richards, R Starkey, W
Source	Medline; PMC
abstract	The pepscan procedure was used to identify betanodavirus B‐cell epitopes recognized by neutralizing mouse monoclonal antibodies (MAbs) and serum samples obtained from sea bass, Dicentrarchus labrax, naturally infected with betanodavirus. Pepscan was performed with a panel of thirty‐four 12‐mer synthetic peptides that mimicked the entire betanodavirus capsid protein. Sea bass serum samples reacted strongly with three regions of the capsid protein comprising amino acid residues 1–32, 91–162 and 181–212. The latter region was also recognized by neutralizing MAbs and coincided with a region of high antigenic propensity identified by an antigen prediction algorithm. These data suggest that a region of the betanodavirus capsid protein spanning amino acid residues 181–212 may represent a neutralization domain that could potentially be used to inform the development of nodavirus vaccines and immunodiagnostic reagents.
has issue date	2007-06-20(xsd:dateTime)
bibo:doi	10.1111/j.1365-2761.2007.00824.x
bibo:pmid	17584439
has license	no-cc
sha1sum (hex)	07bf54e87a9fa11ef4571742ef96eb7d9e94ab9f
schema:url	https://doi.org/10.1111/j.1365-2761.2007.00824.x
resource representing a document's title	Identification of B‐cell epitopes on the betanodavirus capsid protein
has PubMed Central identifier	PMC7197462
has PubMed identifier	17584439
schema:publication	J Fish Dis
resource representing a document's body	covid:07bf54e87a9fa11ef4571742ef96eb7d9e94ab9f#body_text
is schema:about of	named entity 'performed' named entity 'residues' named entity 'algorithm' named entity 'NEUTRALIZATION' named entity 'SUGGEST' named entity 'MONOCLONAL ANTIBODIES' named entity 'REAGENTS' named entity 'nodavirus' named entity 'procedure' named entity 'protein' named entity 'epitopes' named entity 'Sea bass' named entity 'spanning' named entity 'protein' named entity 'sea bass' named entity 'recognized' named entity 'vaccines' named entity 'nodavirus' named entity 'amino acid residues' named entity 'capsid protein' named entity 'epitopes' named entity 'betanodavirus' named entity 'amino acid residues' named entity 'synthetic peptides' named entity 'capsid protein' named entity 'Molecular Biology' named entity 'porcine reproductive and respiratory syndrome virus' named entity 'serum samples' named entity 'serum samples' named entity 'betanodavirus' named entity 'nucleotide sequence' named entity 'Peptides' named entity 'SARS coronavirus' named entity 'betanodavirus' named entity 'RNA-dependent RNA polymerase' named entity 'sea bass' named entity 'betanodavirus' named entity 'coat protein' named entity 'Serum samples' named entity 'peptide' named entity 'Tetracapsuloides' named entity 'Peptide' named entity 'immunization' named entity 'epitopes' named entity 'epitopes' named entity 'monoclonal antibody' named entity 'peptides' named entity 'epitope' named entity 'infection' named entity 'causing disease' named entity 'Greece' named entity 'betanodavirus' named entity 'coat protein' named entity 'Protein' named entity 'viral pathogens' named entity 'vaccines' named entity 'homology' named entity 'secondary structure' named entity 'human immunodeficiency virus' named entity 'Gadus morhua' named entity 'standard deviation' named entity 'amino acid' named entity 'Capsid protein' named entity 'betanodavirus' named entity 'glycoprotein' named entity 'peptides' named entity 'antibodies' named entity 'Betanodavirus' named entity 'capsid protein' named entity 'protein' named entity 'genome' named entity 'genotype' named entity 'serum samples' named entity '0.49' named entity 'sea bass' named entity 'nucleotide sequence'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software